Abstract

Hepatocellular carcinoma (HCC) is a rare primary malignant tumor of the liver in childhood accounting for 20% to 33% of cases. Important prognostic factors are the presence of distant metastases and tumor unresectability. Currently there are no proven curative treatment options for pediatric patients with the abovementioned unfavorable prognostic factors. Authors represent a clinical case report of the HCC development with intra-abdominal metastases in an 8 years old pediatric patient. The Lenvatinib therapy with previous cytostatic therapy combined with sorafenib allowed the 6 months control over the tumor process whilst maintaining reasonably good quality of life of a patient.

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