Abstract

The aim of the study is to compare the reproductive outcome of women with familial Mediterranean fever (FMF) and a control sample. An observational cohort study compares the outcomes in 251 women with FMF to 312 without FMF. A study of perinatal outcomes showed that weight, height and neonatal status assessment at birth were comparable in both groups. The average body weight of the newborn was 2800±500g in the FMF group and 2770±580g in the control group (p≤0,05), the average height was 48±2,5cm and 49±3,0cm (p≤0,001), respectively. Apgar score in the first and fifth minutes of life: 7,6±0,6 and 7,7±0,7 points, (p≤0,05) and 8,4±0,2 and 8,7±0,5 points, (p≤0,01) respectively. Fetal distress was detected in 2,0% in group 1 and in 2,5% in group 2; CDF – 1,6% and 2,6, PS – 31,5% versus 45,5% (p≤0,001); postpartum hemorrhage – 0% and 0.8%; maternal mortality – 0% and 0%, respectively. Perinatal outcomes were comparable in patients with Familial Mediterranean fever and control group.

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