Abstract

Purpose. To evaluate the anatomical and functional results of surgical treatment of patients with large macular holes using the developed modification of the method of inverted internal limiting membrane flap. Material and мethods. The study included 72 patients (72 eyes) with a diagnosis of “full thickness macular hole” with a macular defect diameter of more than 400µm. The patients underwent a complete ophthalmological examination, including optical coherence tomography and microperimetry. The average age of patients was 67.8 ± 4.7 years The average diameter of macular holes according to OCT was 561.6 ± 123.6µm, the best-corrected visual acuity 0.12 ± 0.08. Results. All patients underwent endovitreal intervention by one surgeon according to the developed method. According to optical coherence tomography, in 98.6 % of cases (71 out of 72 patients), macular holes closure was observed 2 weeks after surgery. All patients noted an improvement in visual functions in the postoperative period. The best corrected visual acuity 2 weeks after the operation was 0.4 ± 0.08, as a rule, the maximum visual acuity was achieved after 6 months (0.5 ± 0.08). Conclusions. The proposed method showed high efficiency in the treatment of patients with large macular holes, which was confirmed by the data of optical coherence tomography, visometry and microperimetry. Keywords: large macular hole, internal limiting membrane peeling, inverted in-ternal limiting membrane flap.

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