Влияние толщины и сосудистой плотности сетчатки на ее светочувствительность при диабетическом макулярном отеке

Abstract

Purpose: to study the effect of the thickness and vascular density of the retina on its photosensitivity in diabetic macular edema. Material and methods. 9 patients (13 eyes) aged from 26 to 79 years (average age 62.1 ± 16 years) with a diagnosis of diabetic retinopathy (DR), diabetic macular edema (DME) were examined. In addition to the standard ophthalmological examination, a complex of specialized research methods was performed, including microperimetry, optical coherence tomography (OCT) and OCT with angiography (OCT-angio) of the posterior segment of the eye. At the same time, the influence of morphometric parameters on functional changes in the retina in the corresponding segments with a diameter of 6 mm was analyzed. Results. The study was a high inverse correlation relationship in the majority of cases between the parameters of the relevant sectors according microperimetry and OCT and OCT-angio in central zone of diameter 1, 3 and 6 mm and a direct correlation between central retinal thickness by OCT diagnosis and the so-called parameter K, denoting the number of points with sensitivity below 24 dB according microperimetry with a high degree of confidence (p<0.01, p<0.05). Conclusion. According to the results of our study, a direct correlation was found between the vascular density of the superficial and deep capillary plexuses and the parameters of photosensitivity in patients with DME. At the same time, the relationship between the thickness and light sensitivity of the retina is inverse. Key words: diabetic retinopathy, diabetic macular edema, optical coherence tomography, microperimetry, angiography.