МУЛЬТИМОДАЛЬНАЯ ДИАГНОСТИКА У ПАЦИЕНТОВ С КОМПОНЕНТАМИ МЕТАБОЛИЧЕСКОГО СИНДРОМА, ПЕРЕНЕСШИХ ИНТЕРСТИЦИАЛЬНУЮ ПНЕВМОНИЮ, АССОЦИИРОВАННУЮ С COVID-19

Abstract

Introduction. Coronavirus infectious disease caused by SARS-CoV-2 characterized by vast clinical variability. Extrapulmonary complications associated with endothelial damage, thrombosis and impaired regulation of immune responses provide unfavorable impact on the outcome of the disease and rehabilitation opportunities. Also, infection inflict damage to the gastrointestinal tract, hepatobiliary system. A key - roles to avoid aforementioned conditions are proper diagnosis and treatment plan, which should be make as soon as possible among the patients with elements of metabolic syndrome. The aim of the study - analyze the possibilities of multimodal diagnostics in patients with elements of the metabolic syndrome who get infected by SARS-CoV-2. Material and methods. In 41 patients with positive SARS-CoV-2, according to a nasopharyngeal smear study, the elements of the metabolic syndrome such as an increase in body mass index, serum triglycerides, and blood pressure were determined. Dynamic ultrasound of the abdominal cavity organs, CT scan of the chest in the near and distant periods were performed. Results and discussion. In the period 2020 - 2021. in patients with elements of the metabolic syndrome who have suffered of interstitial pneumonia caused by COVID-19, the predominant patterns was diffuse mosaic changes in lung tissue lesions with the spread of changes in lung parenchyma to more than one segment were identified. In a comparative aspect, dynamic multimodal diagnostics of abdominal organs was performed, confirming extrapulmonary complications from the liver: hepatosplenomegaly (p ≤ 0.01), changes of hemodynamics in hepatic vessels in patients with MS (p ≤ 0.05), increased stiffness and formation of liver parenchyma fibrosis in almost 15% (F2- F3). Conclusion. Study confirm the need for careful and long-term monitoring of patients, who are a in group of risk to develop metabolic syndrome with multimodal noninvasive ultrasound control of the condition of target organs.