Кількісні та якісні показники спермограм чоловіків різних вікових груп у нормі та за патологій

Abstract

The indicators of spermograms of men of different ages: younger (20-29 years), middle (30-39 years) and older age groups (40-50 years) with normozoospermia, oligoteratoasthenozoospermia, teratoasthenozoospermia and hypoteratozoospermia were studied. Spermograms were obtained during examination of patients at the “Alternative Clinic” reproductive medicine clinic. Spermograms were evaluated according to the following indicators: volume of ejaculate, viscosity, number of spermatozoa in 1 ml of ejaculate; the total number of sperm in the ejaculate; motility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. Having analyzed the results of spermograms of men of different age groups, we found out that the main indicators of deviations in these spermograms are the mobility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. In order to quantitatively assess the influence of oligoteratoasthenozoospermia, tera­toasthenozoospermia and hypoteratozoospermia and the age factor on the general variabi­lity of spermogram indicators of men of the younger (20–29 years), middle (30–39 years) and older (40–50 years) age groups, we conducted 41 series of univariate and 18 series of two-factor analysis of variance. After conducting a anova analysis, we established that the share of the influence of the studied diseases in the overall variability of the sperm motility index by category B in men of the younger age group is insignificant and amounts to 10 % of the total contribution, instead, the share of the influence of unaccounted factors is increasing, which is 90 % of the total contribution - this may indicate the presence of pathological processes in the reproductive organs of men. The share of the influence of the age factor on the overall variability of such indicators of spermograms as motility of spermatozoa according to category A and B, morphology of spermatozoa (percentage of morphologically normal and degenerate spermatozoa), Farris fertility index and activity and viability of spermatozoa of younger, middle and older age groups is insignificant and is in ranging from 1 to 6 %.