Abstract
Primary CNS germ cell tumors are a heterogeneous group of neoplasms. The incidence of these tumors depends on the geographical location. The risk of CNS GCT is two to threefold higher in Asian / Pacific Islanders compared to Americans. Factors affecting the treatment and prognosis of diseases are the histological characteristics of the tumor, the presence or absence of distal metastases and the level of tumor markers in plasma and CSF. Currently, the most effective treatment option is neoadjuvant chemotherapy followed by a reduced dose and volume of radiation therapy. Depending on the histological characteristics of the tumor, treatment can provide a survival rate of up to 90%.
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