Abstract
The relationship between polypous rhinosinusitis and allergic rhinitis, as well as the formation of tactics for the treatment of exacerbations, is a prominent problem of modern otorhinolaryngology. Changes of the microbiota of the nasal cavity and paranasal sinuses, the addition of a bacterial infection are the risk factors in the development of exacerbations of chronic purulent rhinosinusitis. Of particular difficulty is the formation of bacterial biofilms, as well as the presence of concomitant pathology that worsens the course of an exacerbation of the disease and additional methods of treatment. Our goal was to develop and test in clinical practice a personalized treatment regimen for exacerbations of chronic purulent rhinosinusitis in patients with polyposis rhinosinusitis in combination with allergic rhinitis, as well as to determine its effectiveness. A prospective study was conducted on a cohort of 19 patients with polypous rhinosinusitis in combination with allergic rhinitis. During the study, the bacteriological composition of the microflora of the nasal cavity and paranasal sinuses was assessed, a thorough examination of patients was carried out, treatment was prescribed in accordance with the severity and the developed scheme. Control studies were carried out on the 7th day of the study, if necessary, the treatment tactics were modified. By the 14th day of the study, patients showed normalization of the endoscopic picture, the disappearance of the symptoms of the disease, as well as the restoration of the microflora of the nasal cavity with a decrease in the level of pathogenic and opportunistic microorganisms. Thus, the need for complex diagnostics and personalized treatment in exacerbation of chronic purulent rhinosinusitis in patients with polypous rhinosinusitis in combination with allergic rhinitis was shown, and the effectiveness of the developed treatment regimen was confirmed by both subjective and objective methods.
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