Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of clinical manifestations that can affect the gastrointestinal tract (GIT). The onset of SLE before adulthood affects the clinical presentation, course, and prognosis. The GIT and the hepatobiliary system involvement in SLE with juvenile onset is regarded as an unfavorable prognosis factor with high probability for development of persistent organ disorders, which is life-threatening in some cases. The article analyzes gastroenterological pathology within SLE in children and adolescents, discusses such lesions as lupus enteritis, exudative enteropathy, intestinal pseudo-obstruction, mesenteric vasculitis, pancreatitis and liver damage on the basis of bibliographical data.
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