ОСОБЕННОСТИ ТЕЧЕНИЯ БЕРЕМЕННОСТИ, ПЕРИНАТАЛЬНЫЕ ИСХОДЫ И РЕЗУЛЬТАТЫ ЛЕЧЕНИЯ ТУБЕРКУЛЕЗА У ЖЕНЩИН БЕЗ ВИЧ-ИНФЕКЦИИ

Abstract

The objective of the study is to investigate the specific course of pregnancy, perinatal outcomes and treatment results in HIV negative female patients. Subjects and Methods . Medical files of 109 pregnant tuberculosis patients were analyzed who were followed up in Krasnoyarsk Regional TB Dispensary no. 1 from 2010 to 2014. Results . The part of children prematurely born by mothers ill with tuberculosis was practically compatible with the overall national cohort of live-born children (6.8% in the analyzed group versus 5.7% in the national cohort for 2014). The part of children with congenital abnormalities born by mothers suffering from tuberculosis turned out to be twice lower versus the overall national cohort of live-born children (1.4% versus 3.0% in 2010 and 2.9% in 2014). The efficiency of the main treatment course in pregnant women without multiple drug resistant tuberculosis, of which 3.8 ± 0.3 months of tuberculosis treatment coincided with pregnancy was practically the same as treatment efficiency for the overall cohort of patients in Krasnoyarsky Kray (66.2% in the analyzed cohort versus 60.3-72.7% in the regional cohort for 2010-2014). In the pregnant with multiple drug resistant forms of tuberculosis, treatment efficiency was lower versus the regional cohort (30.4% in the analyzed cohort versus 41.1-60.2% in the regional cohort for 2010-2014).