Abstract

Keywords: acutebronchitis, atopicdermatitis, children, Bronchipret. Acute bronchitisis a topical issue in pediatrics and one of the most common reasons for seeking medical attention. In children with anallergic background, special requirements are made for the treatment of acute bronchitis, as treatment should notincrease the allergy of the body. Objective: to study the effectiveness and safety of the drug Bronchipret syrup in children with acute bronchitis and atopic background. Materials and methods. The study in volved 30 children 3- 7 years old with acute bronchitis with a burdensome anamnesis of allergic diseases. Allergic background was assessed by serum IgE levels in blood serum. During treatment, all children received the drug Bronchipret syrup 3 times a day for 10 days. Repeated clinical examinations of patients were performed for 3, 5, 7 and 10 days from admission to the hospital. Results. Against the background of complex treatment with the inclusion of the drug Bronchipret, the intensity of fever and intoxication syndrome were significantly lower on the 3rd day of hospital treatment and on the 5th day in the vast majority of children disappeared. Improvement in the discharge of nasal and bronchial secretions was observed on the third day of therapy. Increase in eosiophil content wasn’t observed in any child during treatment. Within 10 day softreatment, significant changes in serum Ig E didn’t occur. Thus, at the beginning of the rapy it was in the range of 38.3 ± 1.3 kU / l, after 10 days – 36.8 ± 1.1 kU / l. Conclusions. Thedrug Bronchipret syrup has shown good efficacy and safety, no allergic complications in children with acute bronchitis and allergic background and can be recommended for useinpediatric practice.

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