АССОЦИАЦИЯ СОСУДИСТЫХ КАЛЬЦИНАТОВ МОЛОЧНОЙ ЖЕЛЕЗЫ И ГИПОТИРЕОЗА: описание серии клинических наблюдений и обзор литературы

Abstract

Abstract. Introduction. Currently, mammography is widely used in the routine clinical practice and, along with detecting the changes that may be indicative of breast carcinoma, allows assessing the unaltered breast parenchyma and its feeding vessels with the diameter of at least 0.5 mm, particularly regarding calcifications. Hypothyroidism represents the deficiency of thyroid hormones, which is relatively frequently seen in the clinical routine and associated with multiple unfavorable outcomes. Aim: To present a series of clinical cases where we found typical breast vascular calcifications in female patients at mammography. Materials and Methods. This paper describes 3 patients of this type with long- standing uncompensated hypothyroidism, all having pronounced vascular breast calcifications. Results and Discussion. All the patients had no significant cardiovascular pathologies both at the first detection of vascular calcifications and during their 5-year follow-up. Hypothyroidism is associated with the decreased overall survival as compared to the euthyroid patients, particularly because it also increases the risk of chronic kidney insufficiency, adhesive shoulder capsulitis, senile macular degeneration, myocardial infarction, and chronic cardiac insufficiency. This makes timely identifying such patients very important. Conclusion. Pronounced vascular calcifications at mammography may be the marker of the chronic thyroid insufficiency. Moreover, this phenomenon and the link between such changes and adverse cardiovascular outcomes needs to be clarified in future clarification.