Abstract

The effect of acetylsalicylic acid and acetylsalicylates of (Co2 +), zinc (Zn2 +), nickel (Ni2+) and manganese (Mn2+) at doses of 5 and 10 mg/kg on rat tissue microhemodynamics was studied. It was established that the coordination compounds of metal salicylates demonstrate novel properties and a more pronounced biological effect compared to a parent compound, acetylsalicylic acid. This favors further search for biological and pharmacological activities among newly synthesized coordination compounds of acetylsalicylic acid.

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