Abstract

Background. Currently, intra-articular injections of platelet-rich plasma (PRP) are becoming increasingly popular as a technically simple and effective method of osteoarthritis treatment. However, this clinical case would demonstrate that this procedure could lead to severe complications. Purpose of the study. Our aim is to describe a clinical case in which PRP injections led to the development of a generalized infection resulting in purulent polyarthritis, epiduritis and sepsis in a patient with a previous odontogenic infection. Material and methods. Clinical manifestations, results of laboratory and instrumental studies, anamnesis and medical documentation were analyzed. Results. After intra-articular injection of PRP the patient developed purulent polyarthritis and spondylodiscitis resulting in purulent epiduritis and sepsis. The patient was diagnosed with extensive dental caries which had caused transient bacteremia, and then PRP injections helped to the transfer of infection from the blood to the joint cavities. Conclusions. Before undergoing intra-articular PRP injections the patient should be carefully assessed for the presence of infection.

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