Abstract
Abstract – The neurobiological properties of excitation and inhibition in the central nervous system (CNS) were detected in post-traumatic stress disorder (PTSD) and acute predatory stress in Wistar rats, tested in the elevated plus maze (EPM). Using the EPM in the author's modification and the registration of an extended range of psycho-emotional characteristics it was found a severe insufficiency of excitation and a significant redundancy of inhibition in the CNS during PTSD and acute predatory stress. It was shown that during acute predatory stress the inhibition processes are changed or got damaged primarily and more extensively in comparison with the excitation processes. A new understanding of the excitatory-inhibitory processes of the CNS, obtained by analyzing a set of general neurobiological behavioral changes, gives an idea of the functioning of the brain under stress and highlight potential possibilities for developing conceptually new strategies for treating neuropsychiatric disorders, associated with stress.
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