Abstract
Nanosilver preparation is synthesized in the carriers based on polymer/inorganic hybrids in aqueous dispersion form by in situ synthesis of silver nanoparticles in biocompatible and biodegradable polymer/inorganic hybrid based on silica sol and polyacrylamide. Hydrophilic polymer/inorganic hybrid used as a carrier for silver nanoparticles was synthesized by the developed method of directly grafting polyacrylamide "from" the unmodified surface of silica sol. The size of silver particles in the preparation was <10 nm. Studies have found that single, double and three-fold sprinkling of laying hens of nanosilver in polymer/inorganic hybrid carriers at concentrations of 1.0 and 2.0 mg/l (at doses of 0.2 and 0.4 mg per hen per day) did not affect the consumption of feed, water and egg productivity of poultry. The obtained nanosilver preparation is safe for laying hens and it does not cause disorders of clinical condition, diseases and poultry death during three-fold drinking with 10 days interval. After drinking the preparation of nanosilver to the laying hens at doses of 0.2 and 0.4 mg per head per day with an interval of 10 days, the dose-dependent amount of silver in the manure was increased only after a single drinking and after double and triple drinking, it did not affect the content of silver, copper, zinc, iron and lead. Single drinking of laying hens with a solution of silver nanoparticles in carriers based on polymer/hybrids at a concentration of 1.0 mg/l (0.2 mg per hen per day) increased the silver content in hen manure by 20% compared to the control group, and it did not affect the content of copper, zinc, iron and lead in manure. Nanosilver preparation at a concentration of 2.0 mg/l (0.4 mg per hen per day) increased the silver content by 44% in hen manure on the 10th day only after the first drinking of the preparation and it did not affect the content of copper, zinc, iron and lead compared to the control and with similar data of hens to which the same preparation was given at a concentration of 1.0 mg/l.
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