Abstract

Based on the selected, criteria-based risk phenotypes for chronic lung diseases (CBL), 177 adolescents, 11-17 years old (11.94±0.8 years), during the three-week observational observation, two phenotypic groups (2.3), during their stay in the sanatorium, were prescribed an equivalent set of non-drug therapy, with various additions, halo-therapy (GLT) or speleo therapy (SLT). The dynamics were analyzed, with a comparison of a set of diagnostic indicators, at the beginning and at the end of the course of sanatorium treatment: variability of PSV per week, OFV1, FVC, OFV1/FVC, MOS75-50-25, lung age, electronic auscultation, symptoms (cough, shortness of breath, sputum separation), CO., No., assessment of the quality of life (QOL) according to the SF-10 questionnaire. For phenotype 2 (moderate risk of CBL), there was a better dynamics, weekly variability of PSV, increase in PSV in % of due, severity of respiratory acoustic noise, - when using GLT; at the same time, in the gender decomposition, there was a more pronounced positive dynamics, in boys, in terms of growth of OFV-l, FZHEL-l, OFV1/FZhEL-% and OFV1/FZhEL-% , MOS 25-75-l and MOS50-% of due, -, against the background of GLT. For phenotype 3 (high risk of CKD), less pronounced clinical and functional dynamics were noted. According to QOL, for phenotypes 2 and 3, when supplementing the course of sanatorium treatment with SPT or GLT, both in physical and socio-mental components, both in girls and boys, it was positive. For phenotype 2, QOL improved, with the use of GLT, at p<0.05: according to the parameters of general health, according to the component of physical well-being, it was more noticeable in young men. For phenotype 3, a reliable QOL dynamics was established, according to the dynamics of general health and the social component. In general, young men of phenotypes 2 and 3 reacted better to the additional effects of GLT compared with SPT, which was confirmed by reliable positive dynamics of functional indicators and QOL.

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