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Abstract
The immune system provides resistance of the organism against bacterial and viral infections in the body of the poultry. In the intestinal mucosa of eymeria it was secrete metabolic products, that are toxic to various systems and tissues of turkeys. Eymeria, parasitizing in the gut, inhibit specific phase of immunity presented by antibodies (humoral type), reduce the activity of sensitized cells (cell type), slow down nonspecific phase of immunity, represented by various immune cells. The rapid and complete recovery of functional state of the immune system in turkeys, affected by eymeriozic invasion it was found if brovitatoxide was given if the aggregate of the fruits of milk thistle. Fruits contain group of flavius lignans named «Sylimaryn», acting immune stimulatory for the development of secondary immuno deficiencies state of body.
Highlights
Ukraine has recently slightly reduced the number of breeding and commodity farms of the turkeys growing
The purpose of our research was to study the effect of only brovitatoxide, and with the combined use with the fruits of milk thistle on normalization of the immune system of turkeys by spontaneous affection of eymeriozic invasion
Over 5 days after clinical recovery the number of leukocytes was 9% greater than control, which indicates the presence of inflammation of the mucous membranes in areas where eymeria parasitize
Summary
Ukraine has recently slightly reduced the number of breeding and commodity farms of the turkeys growing. The importance of this issue in terms of efficiency of early diagnosis and the development of effective therapy is emphasized in a number of scientific papers (Mashke and Zakharov, 2002; Bohach and Taranenko, 2003; Timofeev, 2004; Khariv, 2011). In early phylogenetic development for turkey poults there are different stress factors – inadequate feeding, inadequate housing conditions, bacterial infections, worms and protozoon invasion. This leads to decrease in body's natural resistance and inhibition of bone marrow hematopoietic function (Kotel'nikov, 1991; Dakhno et al, 2001). The disadvantage of these drugs is that they are introduced parenterally, as is well known, poultry up to 3 months of age hardly carry over parenteral injection
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