Опыт использования возможностей лазерной спекл-флоуграфии при макулярном отеке на фоне окклюзий ретинальных вен (предварительное сообщение)

Abstract

Purpose. To evaluate the features of blood flow in the optic nerve disc (OND) in patients with macular edema on the background of retinal vein occlusions (RVO). Material and methods. The study included 30 patients (30 eyes) with macular edema on the background of acute respiratory viral infections. Their age ranged from 38 to 84 years (on average 60 ± 10.5 years). There were 11 men and 19 women among them. The control group included 15 somatically healthy patients with no vascular pathology of the eye (30 eyes). In addition to the standard ophthalmological examination, all patients underwent a study of the state of retinal blood flow by laser speckle-fluorography. To assess the blood circulation of the vessels around the optic nerve disc, a circular marker was installed, after which the software allowed to evaluate the following parameters: the average value of the blurriness of the image of the blood vessel area (MV); the average value of the blurriness of the image of the tissue area (MT); the average value of the blurriness of the image of the entire measured area (MA); the average value of the blurriness of the image of the area of blood vessels, reduced by the same indicator related to the area of tissue – this indicator reflects the blood flow in the retinal vessels (MV–MT). Results. In the course of the study, a significant decrease in the velocity parameters of the blood flow of the optic disc region was revealed in patients of the main group relative to the control group. The parameters MV–MT, MV, MT decreased by 20, 22, 26 % in the main group relative to the control group (p < 0.001). The most pronounced decrease was revealed for the MA indicator. This parameter decreased by 32 % in patients with retinal vein occlusions (p < 0.001). Conclusion. In our pilot study, a statistically significant decrease in the average blur speed was revealed in patients with macular edema on the background of ORV, which indicates a violation of blood flow and indicates the prospects of using the method in clinical practice. Keywords: laser speckle-fluorography, average blurring rate, retinal vein occlusion, macular edema, chorioretinal blood flow.