Abstract
Objective of the research: comparison of two methods of initial respiratory support: high-frequency positive pressure ventilation (HFPPV) and conventional mechanical ventilation (CMV) in extremely low birth weight (ELBW) infants. Materials and methods: prospective, randomized, pilot study, carried out in one level III perinatal center. Thirty-two ELBW babies was randomly separated in two groups: group A – HFPPV (n=17), group B – CMV (n=15). Results: the recovery time for heart rate more than 100 beats per minute in group A was faster than in group B (33,9 seconds vs. 79,2 seconds, p=0,002). Maximum FiO2 for the period of staying in hospital was significantly higher in group B (0,37 vs. 0,73, p<0,001). Mortality in CMV group was significantly higher (0% versus 27%, p=0,038). Conclusion: HFPPV in the delivery room in ELBW babies effectively restores heart rate, reduces the risk of lungs injury and the risk of death before discharge from the hospital.
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