Влияние кардиоваскулярной и метаболической патологии на сроки развития профессиональной хронической фтористой интоксикации у работников алюминиевого производства

Abstract

With the aim of studying the effect of disorders of carbohydrate and lipid - tion exchange and associated cardiovascular disease at the time of development of occupational fluorosis assessed the prevalence of this disease among workers in aluminum production. A significant dissociation of carbohydrate and lipid metabolism indices against the background of high prevalence of overweight, obesity, arterial hypertension in workers in contact with elevated concentrations of inorganic fluorine compounds was established in comparison with patients of the comparison group who are not exposed to toxic substances (р=0,003, t=3,159). The increase in fasting glycemia was revealed already with the work experience of up to 10 years, which can testify to the danger of early development of type 2 diabetes in workers of aluminum production and the need for timely preventive measures in this category of workers. At the same time, patients with occupational fluorosis had significantly higher prevalence of carbohydrate metabolism disorders compared to trained workers without occupational fluorosis (р=0,006). It was revealed that professional fluorosis develops significantly earlier in workers with concomitant cardiovascular disease and metabolic changes.