Abstract
The relevance is explained by the need to determine the list of indicators of public health and the functioning of the health system, which are influenced by biological, geopolitical and man-made challenges, considered as the transition of one of the determinants that determine the state of public health to an extreme state, and the rationale for their changes for timely organizational and managerial decisions. O b j e c t i v e : conduction an expert assessment and substantiate the impact of global biological, geopolitical and technogenic challenges on population health indicators and healthcare system. M a t e r i a l s a n d m e t h o d s . Based on the content analysis of domestic (n=14) and foreign publications (n=30), using expert assessment, a list of parameters was compiled that determine the impact of biological, geopolitical and technogenic challenges on population health indicators and healthcare system. R e s u l t s . The directions of changes in such health indicators of the population as primary and general morbidity according to the data of the appeal, mortality of the population in different age groups, life expectancy, physical development, disability and health groups, and such indicators of the structure of consumption of resources of the health system as access to medical care, the burden on medical workers, changes in financial costs are determined, as well as the risks of its sustainable functioning. D i s c u s s i o n . The theoretical substantiation of the vector of the impact of a particular type of global challenge to society on the state of indicators of key determinants of public health, allows for timely development of a set of preventive measures taking into account the models of response of determinants, improving approaches to their planning and organization both for the industry as a whole and at the level of a medical organization and the region.
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