Abstract
Purpose: to substantiate the choice of an antibacterial agent when using the puncture method for the treatment of chronic sinusitis in HIV-infected patients. Material. Microbiological studies were carried out in 108 HIV-infected patients with chronic sinusitis. The microbiological spectrum of pathogens of chronic inflammation of the paranasal sinuses in HIV-infected persons was determined, as well as the sensitivity of microorganisms to antibacterial agents. Results. The most frequently detected microorganisms in HIV-infected patients with chronic inflammatory pathology of the paranasal sinuses are gram-positive cocci (89,7 ± 2,9), including staphylococci (75,7 ± 4,1) and streptococci (14,0 ± 3,3). The verified microflora showed low sensitivity to antibiotics of the penicillin group (less than 65 % of sensitive strains), which limits the possibility of their use. A method for the treatment of chronic sinusitis in HIV-infected patients has been developed, based on the introduction into the sinus of an etiologically substantiated drug with a prolonged action. Conclusion. The revealed features of the spectrum of pathogens and the sensitivity of microorganisms in chronic sinusitis in HIV-infected patients made it possible to scientifically substantiate and develop a treatment method based on the introduction of a polyethylene oxide-based ointment containing chloramphenicol and methyluracil into the sinus.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
