Морфометрическое исследование клеток соединительной ткани склеральных лоскутов при первичной глаукоме в зависимости от уровня ретенции внутриглазной жидкости

Abstract

In scleral flaps resected during anti-glaucoma surgeries in 60 patients with 6 different forms of primary glaucoma, the content of connective tissue cells — matrix-producing and infi ltrate elements — was studied using comparative morphometric analysis. The scoring of the proximal and distal sclera zones separately with 2 forms of glaucoma with a pretrabular level of the hydrodynamic block revealed a signifi cantly higher number of matrix-producing cells in congenital glaucoma compared with angle-closure one. Analysis of 4 forms of glaucoma with a trabecular block showed a significantly higher content of matrix-producing cells up to the distal drainage pathways in pigmentary and pseudoexfoliation glaucoma which contributes to the development of accelerated retention of the aqueous humor outflow. The polymorphic pattern of structural changes in the connective tissue of the eye drainage system determines the feasibility of using a differentiated algorithm when planning the surgical treatment volume.