Влияние витаминов и микроэлементов на метаболические показатели лиц с эутиреоидной гипертрофией щитовидной железы и избыточной массой тела

Abstract

The article is devoted to studying of influence of additional vitaminization (fortification) in the patients with the euthyroid hypertrophy of the thyroid gland and overweight on lipid and mineral metabolism, the concentration of urinary iodine and thyroid volume. The study involved 10 patients aged from 13 till 46 years with the overweight and euthyroid hypertrophy of the thyroid gland. Out-patient examination and treatment in the therapeutic department of Endocrinological scientific centre of RAMS was carried out for all patients. The patients were on a low-calorie diet (1500 kcal). Vitamin and microelement complex “Daily Care Pack” (USA) was used for additional fortification. Before taking vitamin and microelement complex and 12 days after its graduation, it was measured patient´s growth and body weight and calculated assessed body mass index. Level of cholesterol, triglycerides, lipoproteins high and low density, level of mineral elements (sodium, potassium, phosphorus, calcium) were estimated in peripheral blood. An iodine concentration in urine and a thyroid gland volume were measure too. It is shown that the result of additional vitaminization (fortification) and microelements taking was a body weight decreasing for all patients. In the peripheral blood, a decrease of cholesterol, triglycerides, and lipoproteins, and this decline was greater than the higher was the initial degree of obesity. The content of microelements in the blood of patients before and after taking the vitamin and microelement complex has not changed. The tendency to the increase of the concentration of iodine in urine was revealed, however, additional intake of iodine deficiency in the vitamin-mineral complex practically no effect on the amount of the thyroid gland. Thus, additional fortification against the background of hyper-high-calorie diet in the persons with euthyroid hypertrophy of the thyroid gland and overweight accompanied by a decline in body mass index, the positive dynamics of lipid metabolism, stabilization of mineral metabolism, but it almost doesn’t have any impact on the volume of the thyroid gland.