Вплив елімінаційної дієти на функціональний стан шлунково-кишкового тракту та печінки в жінок фертильного віку із симптомним аденоміозом

Abstract

The existence of food intolerances disrupts the work of the gastrointestinal tract and the liver, the symptoms of which are largely similar to those of adenomyosis. Purpose - to investigate the effect of the elimination diet on indicators of the functional state of the gastrointestinal tract and liver of women having symptomatic adenomyosis. Materials and methods. 120 women with symptomatic adenomyosis were divided into 4 groups: the Group I - 30 women who were treated with dienogest; the Groups ІІ, ІІІ and IV - 30 women each, who were prescribed an elimination diet taking into account the identified type of food intolerance. A comprehensive clinical examination, coprological examination, and ultrasound steatometry of the liver were performed. Statistical data was processed by the SPSS 21 program. Results. Compared with women of the Group I, patients of the Groups II, III, and IV showed a decrease in the pain symptoms of adenomyosis, the frequency of complaints from the digestive tract, amylorrhea, steatorrhea in feces, and markers of the inflammatory process in the intestine, as well as the frequency and severity of liver steatosis. Conclusions. The elimination diet, taking into account the identified type of food intolerance, has a positive effect on well-being, the functional state of the gastrointestinal tract and reduces the symptoms of the disease of childbearing age women with adenomyosis. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author.