Влияние метаболического синдрома на изменение показателей микроэлементного статуса и системы перекисного окисления липидов у пациентов с вульгарным псориазом

Abstract

Aim. To study the effect of metabolic syndrome on changes in the indicators of trace element status and lipid peroxidation system in patients with psoriasis vulgaris. Materials and methods. In the framework of this work, 80 patients were examined with a diagnosis of vulgar psoriasis (group I without metabolic syndrome, group II with metabolic syndrome). The study of the trace element status, the serum content of 25-OH hydroxycalciferol, alpha– tocopherol acetate, as well as the state of the lipid peroxidation system were carried out. Results. in patients with metabolic syndrome, were discovered: a decrease in the indicators of trace element status and vitamins, an increase in the overall oxidative capacity of the blood, an increase in the level of oxidative low-density lipoproteins, as well as a decrease in the overall antioxidant activity of the blood. Conclusion. The obtained data allows to develop recommendations for the management and treatment of patients with vulgar psoriasis by correcting the microelement status and vitamins, which will reduce the influence of metabolic syndrome on the course of the psoriatic process at an early stage.