Abstract

When producing aquaculture products in conditions of increased planting densities of aquatic organisms, it is not always possible to avoid various diseases and injuries. The use of therapeutic baths and feeds often does not al-low to achieve a positive effect. Therefore, the use of cyclodextrin nanosponge with therapeutic and prophylactic agents included in their cavity will allow a targeted effect on the bioavailability of substances and the formation of productive indicators of hydrobionts already since early postnatal ontogenesis. All this will contribute to the improvement of industrial technology for growing table and valuable fish species, characterized by higher survival and productivity. The antibiotic levofloxacin, a broad-spectrum antimicrobial bactericidal agent of the fluoroquinolone group, was chosen as a therapeutic EDN agent. There is presented information on the effect of the complex of β-cyclodextrin with levofloxacin on the lethal qualities of a Russian and Siberian sturgeon hybrid of different live weight. The influence of this complex on the pre-slaughter mass, the mass of individual internal organs, the fatness coefficient, the indices of the internal organs of hybrid individuals was studied according to two stages of the experiment performed in the laboratory “Progressive Biotechnologies in Aquaculture” of Vavilov University. The results of the control slaughter demonstrate the highest values for the indicators in individuals of the 2nd experimental group treated with the main diet at the first stage of the complex chitosan-β-cyclodextrin in various dosages of levofloxacin. Its results exceeded the control in the muscle mass, fatness coefficient, muscle tissue index, respectively. Thus, there was no negative effect of the β-cyclodextrin complex with an antibiotic on the functional state of internal organs and tissues of fish. The results obtained expand the information about the cultivation of sturgeon fish in industrial conditions using cyclodextrin nanosponge.

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