Особливості синдрому взаємообтяження за коморбідності пептичної виразки шлунка, ДПК та захворювань тканин пародонту у осіб із незнімними зубними протезами

Abstract

The comorbid course of peptic ulcer of the stomach, duodenum and periodontal disease indicates common pathogenetic mechanisms of their development and progression. However, researchers do not always take into consideration the influence of dentures, including fixed ones, made of different materials on the course of these diseases. The aim of the study was to investigate the features of the clinical course of periodontal disease in patients with peptic ulcer in the presence of dental prosthetics and without it. To solve the goal and objectives, a study of periodontal tissue in 177 patients with peptic ulcer was performed. Patients were divided into 4 groups depending on the presence of dentures and their structural material: 1st group consisted of 43 people without dentures, 2nd group consisted of 65 people, who had fixed metal dentures: stamped and solid structures, 3rd group – 42 patients with fixed metal-ceramic dentures, and 4th group – 27 people with fixed ceramic dentures. The control group consisted of 20 healthy individuals of the appropriate age. Statistical processing of the material was performed using modern methods of variation statistics. It was found that the prevalence of periodontal disease in patients with peptic ulcer of the stomach and duodenum without dentures and in the presence of fixed dentures differed by 13.8 % (p<0.05). Among the groups of patients with fixed dentures, the highest prevalence of chronic generalized periodontitis of I and II stages of severity was found in the group of patients with fixed metal dentures (60.0% and 29.2%, respectively), which was higher in patients with fixed ceramic dentures in 1.6 times and 2.6 times, respectively (p<0.05). The presence of metal-containing dentures in the oral cavity also adversely affected the course of peptic ulcer of the stomach and duodenum, as it contributed to the development of larger ulcerative defects than in the group without dentures (p<0.05).