РЕЗУЛЬТАТЫ ПРИМЕНЕНИЯ ПРЕПАРАТА НАПРАВЛЕННОЙ БИОКОРРЕКЦИИ И ПРЕПАРАТА, СОДЕРЖАЩЕГО ЛАКТОФЕРРИН, В КОМПЛЕКСНОМ ЛЕЧЕНИИ ХРОНИЧЕСКОГО ГЕНЕРАЛИЗОВАННОГО ПАРОДОНТИТА У ПАЦИЕНТОВ С ПЕРВИЧНЫМ ГИПОТИРЕОЗОМ

Abstract

Subject In the traditional complex treatment of inflammatory periodontal diseases, antibacterial, antiseptic and anti-inflammatory agents are of paramount importance. These products allow you to obtain not only a positive clinical result, but can also manifest their negative properties, having an ambiguous effect on the microbiome of the oral cavity and periodontal tissue. The use of targeted biocorrection drugs and immunocorrectors has a significant local anti-inflammatory effect with minimal side effects. Their use in the complex treatment of chronic generalized periodontitis has not been studied enough.
 Aim. To evaluate the effectiveness of using a targeted biocorrection drug and a phytocomplex with lactoferrin in the complex treatment of chronic generalized periodontitis in patients with primary hypothyroidism.
 Material and methods. We observed 90 patients with the main diagnosis of primary hypothyroidism aged 44–59. The patients were divided into 3 groups: in group No. 1, 30 patients received traditional primary periodontal therapy, in group No. 2, 30 patients in whom this therapy was combined with a directed biocorrection drug, in group No. 3, 30 people for whom traditional primary periodontal therapy was combined with a directed biocorrection drug and a drug containing lactoferrin. The comparison group included 30 gender and age-matched patients with chronic generalized periodontitis without thyroid pathology. All patients underwent clinical, X-ray and index evaluation of periodontal tissues. 
 Results. In patients of group No. 1, after traditional treatment, clinical and index evaluation data indicated the persistence of inflammatory processes in periodontal tissues. In groups No. 2 and No. 3 on the background of traditional treatment and additionally administered.
 Conclusions. The addition of a traditional treatment regimen for chronic generalized periodontitis with a targeted biocorrection drug and a drug containing lactoferrin is justified and effective.