Abstract

This work presents the effects of multimodal anesthesia with neuraxial blockade on the basic
 parameters of central hemodynamics in patients operated for lung tumors, revealed by method of terapolar
 rheovasography by Kubicek (systolic blood pressure, diastolic, average heart rate, ejection fraction, minute
 volume of blood circulation, cardiac index, oxygen delivery index, the index of the total peripheral vascular
 resistance), as well the effects on acid‐base balance of arterial blood in the immediate post‐operative period.
 The level of antinociceptive protection was assessed by visual analogue scale. Comparison of results of patients
 operated by means of multimodal anesthesia and the patients, operated in an inhalation intravenous
 anesthesia with artificial lung ventilation and peri‐operative analgesia by opioid analgesics has revealed that
 the hemodynamic profile of the first group of patients is characterized by stability of the basic parameters
 such as blood pressure and heart rate, the lack of a pronounced reduction of the ejection fraction and stroke
 volume of the heart, despite vasoplegia caused by epidural blockade. The level of partial oxygen tension of
 arterial blood was decreased in the early postoperative period, but it was in the normal limits and he was
 statistically significantly higher than in the comparison group that can help reduce the risk of post‐operative
 complications. Significantly lower level of pain indicates adequate antinociceptive protection of patients.

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