Випадки ізольованого аспергильозу шкіри і нігтів та вторинного аспергильозного ураження шкіри, зумовлені професійним чинником. Симптом «засушеного листя» за аспергильозу нігтів

Abstract

Cases of aspergillosis (A.), both isolated lesions of the skin and nails, and secondary skin lesions as a result of complications of invasive aspergillosis of the lungs and intestines, can be considered occupational, since there is a clear connection with the direct professional activities of the patients. it was found. It can be assumed that A. of the skin and nails in dermatological practice occurs more often than is diagnosed, especially since at the present stage the total number of patients with fungal infection is increasing. The goal is to share the experience of clinical and laboratory diagnostics and effective treatment of patients with isolated lesions of the skin and nails due to aspergillosis. Materials and methods. A clinical case of skin damage due to invasive aspergillosis (lungs and intestines) is presented, as both cases are caused by professional factors. Patients were examined in detail with the use of microscopic and mycological (sowing material on a nutrient medium) research. Results and conclusions. When diagnosing, the professional background of the patients should be taken into account. The clinical «symptom of dried leaves» proposed by us is likely to be of significant importance in establishing the clinical diagnosis of onychomycosis caused by A.flavus, and which can serve as a differential sign for other fungal infections of the nails. Our experience confirms the effectiveness of treating A. skin and nails using the «pulse therapy» method with Orungal and confirms its increase under the condition of a combination of systemic action and local antifungal activity of the drug Cidipol.