Abstract

Корригирующее влияние ингибиторов ангиотензинпревращающего фермента на суточный профиль артериального давления и сомнологические характеристики у пациентов пожилого возраста с сочетанной кардиальной патологией

Highlights

  • In recent years, a particular approach to the treatment of elderly patients with combined cardiac pathology has been gaining importance

  • This study aimed to study the corrective effect of ramipril on the daily blood pressure profile (ABMP), its circadian biorhythms, and somnological characteristics in elderly patients with a combination of arterial hypertension (AH) and coronary artery disease (CAD)

  • In the 1st comparison group, the number of patients with functional class (FC) I angina pectoris (AP) increased by 39.9 %, the duration of ST segment depression according to the Holter ECG decreased to 1.3±0.08 min (∆=–35.6 %; p=0.09), the need for nitroglycerin decreased from 2.39±0.19 to 1.25±0.17 per week (∆=–47.7 %; p=0.03)

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Summary

Introduction

A particular approach to the treatment of elderly patients with combined cardiac pathology has been gaining importance It is aimed at adequate antihypertensive therapy and correction of chronologically occurring circadian biorhythms to study the curative effect of ramipril on the daily blood pressure (BP) profile and somnological characteristics of elderly patients with arterial hypertension (AH) and coronary artery disease (CAD). П. КОРРИГИРУЮЩЕЕ ВЛИЯНИЕ ИНГИБИТОРОВ АНГИОТЕНЗИНПРЕВРАЩАЮЩЕГО ФЕРМЕНТА НА СУТОЧНЫЙ ПРОФИЛЬ АРТЕРИАЛЬНОГО ДАВЛЕНИЯ И СОМНОЛОГИЧЕСКИЕ ХАРАКТЕРИСТИКИ У ПАЦИЕНТОВ ПОЖИЛОГО ВОЗРАСТА С СОЧЕТАННОЙ КАРДИАЛЬНОЙ ПАТОЛОГИЕЙ. Chronic sleep disorders can significantly aggravate the CVD course [5] In this regard, an individual approach to cardiac patients’ treatment is gaining importance, aimed at compensating for the underlying disease, and correcting circadian biorhythms

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