This study focuses on the performance of various turbulence models in predicting hemodynamic variables within a patient-specific geometry of the Brachiocephalic trunk exhibiting a severe stenosis. Numerical simulations employing Reynolds-averaged Navier-Stokes (RANS) and Large Eddy Simulation (LES) models were conducted, comparing four RANS with two LES models. Results indicated significant differences in turbulent structures between RANS and LES models, with the k-ω RANS model closely approximating LES throughout the cardiac cycle. The velocity and Turbulent Kinetic Energy (TKE) results were consistent in the stenosis region due to the proximity to the inlet and plug flow conditions. However, notable disparities were observed in bifurcation and outlet regions. Time-Averaged Wall Shear Stress (TAWSS) comparisons revealed that the k-ω-based models provided closer agreement with LES, particularly in atherosclerosis-prone areas. The study highlights the limitations and strengths of each turbulence model, emphasizing the importance of model selection in simulating complex cardiovascular conditions. While RANS models demonstrated computational efficiency, their accuracy varied across regions. The effectiveness of the k-ω model in capturing the intricacies of such a complex flow field suggests its potential as a reliable and accurate tool for simulating physiological conditions with strong curvature and advanced stenosis.
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