Fish Oil Research Articles

Omega-3-Enriched Fish oil reduces the chemotherapy-induced peripheral neuropathy in mice.

Omega-3-Enriched Fish oil reduces the chemotherapy-induced peripheral neuropathy in mice.

Integration of lipidomics and flavoromics reveals the lipid-flavor transformation mechanism of fish oil from silver carp visceral with different enzymatic hydrolysis.

Integration of lipidomics and flavoromics reveals the lipid-flavor transformation mechanism of fish oil from silver carp visceral with different enzymatic hydrolysis.

Comprehensive lipidomics and flavoromics reveals the accelerated oxidation mechanism of fish oil from silver carp (Hypophthalmichthys molitrix) viscera during heating.

Comprehensive lipidomics and flavoromics reveals the accelerated oxidation mechanism of fish oil from silver carp (Hypophthalmichthys molitrix) viscera during heating.

Transcriptomic analysis reveals the hepatopancreas metabolic mechanisms of mud crab Scylla paramamosain fed diets with terrestrial animal fat sources replacing fish oil.

Transcriptomic analysis reveals the hepatopancreas metabolic mechanisms of mud crab Scylla paramamosain fed diets with terrestrial animal fat sources replacing fish oil.

Effects of dietary fatty acids on growth performance, oxidation status, fatty acid and phospholipid profiles of razor clam Sinonovacula constricta.

Effects of dietary fatty acids on growth performance, oxidation status, fatty acid and phospholipid profiles of razor clam Sinonovacula constricta.

Unsaturated fatty acids enhance mitochondrial function and PGC1-α expression in brown adipose tissue of obese mice on a low-carbohydrate diet.

Unsaturated fatty acids enhance mitochondrial function and PGC1-α expression in brown adipose tissue of obese mice on a low-carbohydrate diet.

Autophagy and Endoplasmic Reticulum Stress-Related Protein Homeostasis Links Palmitic Acid to Hepatic Lipotoxicity in Zebrafish (Danio rerio), Counteracted by Linoleic Acid.

Autophagy and Endoplasmic Reticulum Stress-Related Protein Homeostasis Links Palmitic Acid to Hepatic Lipotoxicity in Zebrafish (Danio rerio), Counteracted by Linoleic Acid.

Comparative study of extraction methods for nutritional and safety assessment of fish oils from Heterotis niloticus co-products

Comparative study of extraction methods for nutritional and safety assessment of fish oils from Heterotis niloticus co-products

Performance and emission characteristics of fish oil methyl ester in direct injection diesel engine with hydrogen enrichment - an experimental approach

Performance and emission characteristics of fish oil methyl ester in direct injection diesel engine with hydrogen enrichment - an experimental approach

The relationship of fish oil supplements and plasma fatty acids with lung function decline.

Fish oil supplements and plasma fatty acid levels were reported to be associated with lung function. We aimed to investigate the association of fish oil supplements and plasma fatty acids with lung function. We included 248,133 participants with complete data on relative index of plasma fatty acids from the UK Biobank. Linear regression models were used to investigate associations of fish oil supplements and plasma fatty acids with pulmonary function. Mediation analysis was performed to identify the potential mediating role of plasma fatty acid. All analyses were multivariable-adjusted. Higher lung function was observed in fish oil users (14.59ml for FEV1 and 17.92ml for FVC). We found that each 1-unit increment of plasma PUFA, omega-3, omega-6, DHA, LA, and PUFA/MUFA were positively associated with lung function (6.74ml, 6.15ml, 5.81ml, 22.23ml, 7.44ml, and 66.67ml for FEV1, respectively; 9.04ml, 3.39ml 8.63ml, 25.51ml, 9.53ml, and 93.02ml for FVC, respectively), while SFA and MUFA were inversely associated with lung function (-8.74ml and -8.19ml for FEV1, respectively; -10.44ml and -11.83ml for FVC, respectively). Omega-6/omega-3 only showed a negative association with FEV1 (-1.17ml). Mediation analysis suggested that plasma fatty acids partly mediated the associations between fish oil supplements intake and lung function, mainly DHA (34.70% and 31.50% for FEV1 and FVC, respectively). We provided evidence that fish oil supplements and plasma fatty acids were both associated with lung function parameters, and the positive association between fish oil intake and lung function was mainly mediated by DHA.

N-3 polyunsaturated fatty acids-enriched fish oil attenuates chronic alcohol-induced liver injury via a mechanism involving the upregulation of Retsat.

n-3 polyunsaturated fatty acids-enriched fish oil attenuates chronic alcohol-induced liver injury via a mechanism involving the upregulation of Retsat.

Multivariate analysis of DTMS data for elucidating the chemistry behind soft and dripping paint

The problem of soft and dripping oil paint in mid-20th-century paintings was investigated using high-resolution direct temperature-resolved mass spectrometry (DTMS) and multivariate data analysis techniques. Nineteen paintings by Asger Jorn, Karel Appel, Pierre Alechinsky and Jean-Paul Riopelle were examined, and selected areas were tested for material properties and water sensitivity. Samples were taken from these areas and subjected to DTMS, and the data collected were analysed with principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA). PCA loadings showed grouping of variables belonging to similar chemical structures, but the scores showed only clear clustering of samples classified as solid and healthy. The other categories showed large variability in chemical composition. No clustering on water sensitivity was found. With PLS-DA, chemical markers were detected for the solid and healthy samples that are correlated to the presence of fish oil. Further investigation showed strong indications for the presence of chemical components related to fish oil in many samples from the other categories as well. Earlier hypotheses on the issue of soft and dripping oil paint, based on observations on a single or small group of paintings, could not be confirmed. In this study, it was also shown that using low resolution DTMS may lead to incorrect conclusions, because different chemical components with the same nominal mass can be anti-correlated.

Effects of patin fish-based nutritional intervention on biochemical and physiological recovery in malnourished rats: An in vivo study and its implications for clinical nutrition

Malnutrition is a major global health concern, especially in developing countries. Although patin fish oil and protein offer benefits, their individual and combined effects on maternal physiology remain unclear, particularly during early pregnancy. The aim of this study was to assess the effect of patin-based nutritional intervention on total serum protein, albumin, hemoglobin levels, body weight during pregnancy, body weight during lactation, heart rate, respiratory rate, body temperature, external appearance, behavioral activity, and milk production in malnourished rats. An in vivo study was conducted using Rattus norvegicus rats. The rats were divided into six groups: (1) healthy control, receiving standard feed; (2) malnourished control, receiving an 8% low-protein diet; (3) malnourished group, receiving standard feed; (4) malnourished treated with patin oil; (5) malnourished treated with patin meat; and (6) malnourished treated with a combination of patin oil and meat. The treatment consisted of 21 days during pregnancy and 23 days during lactation, for a total of 44 days. Our data indicated that patin-based intervention significantly increased total protein (p=0.044), albumin (p=0.001), and hemoglobin levels (p=0.034) compared to malnourished control group. The malnourished animals treated with patin oil showed the highest increases in total protein (1.67%), albumin (17.75%), and hemoglobin (24.26%). Body weight gain improved significantly in patin-treated group in both pregnancy (p=0.032) and lactation (p<0.001) compared to the malnourished control, with the highest gains observed in the patin oil group. Milk production also increased significantly (p<0.05), reaching its peak in the patin oil and meat combination group (6.97 g). Physiological parameters, including heart rate (p=0.021), respiratory rate (p=0.025), and body temperature (p=0.023), were significantly different among groups, of which patin oil and meat groups had the most optimal parameters compared to malnourished control group. In conclusion, patin-based nutritional intervention effectively enhances protein metabolism, hematological parameters, and physiological health in malnourished maternal rats, with patin oil demonstrating the most pronounced effects.

Effects of Replacement of Fish Oil with Black Soldier Fly (Hermitia illucens) Oil on the Growth Performance and Biochemical Composition of the Flesh of Nile Tilapia (Oreochromis niloticus) Fry

The black soldier fly (Hermetia illucens) is a promising insect species for use in aquaculture feeds due to its high protein and fat content, with a fatty acid profile primarily consisting of saturated and medium-chain fatty acids. In this experiment, fish oil was replaced with black soldier fly (BSF) oil in varying proportions to evaluate its effect on the growth and biochemical composition of Nile tilapia flesh. Three experimental diets designated R1, R2, and R3 were formulated, replacing 50% and 100% of fish oil with BSF oil. The best results in terms of growth performance and feed efficiency were observed with the R2 diet (50% fish oil replacement), which yielded the following average values: final mean weight (0.42 ± 0.05 g), absolute mean weight gain (0.34 ± 0.05 g), specific growth rate (4.14 ± 0.31%/day), feed conversion rate (2.45 ± 0.74), and protein efficiency coefficient (1.07 ± 0.15). Regarding the biochemical composition of the flesh, there were no significant differences in protein and ash content across the experimental diets, with the following respective values: 17.89 ± 1.49%, 17.29 ± 1.81%, and 16.78 ± 1.83% for protein, and 5.30 ± 0.39%, 4.99 ± 0.47%, and 4.59 ± 0.59% for ash content in diets R1, R2, and R3. However, a significant difference in lipid content was observed between the R2 diet and the R1 and R3 diets, with values of 4.85 ± 0.74, 3.44 ± 1.42, and 3.14 ± 1.27, respectively.

Effects of black soldier fly larvae with and without algal oil on sensory and physical-chemical properties of Chinook salmon fillets

Abstract The rising global demand for seafood products has increased the need for aquafeed ingredients from both traditional and novel sources, as fishmeal and fish oil production cannot significantly expand to support the industry growth. In light of this challenge, our study investigated the feasibility of the partial replacement of fishmeal and fish oil by black soldier fly larvae meal (Hermetia illucens, BSFLM), with and without supplemental algal oil (AO), in diets for Chinook salmon (Oncorhynchus tshawytscha). The control diet (Diet 1) contained higher amounts of fishmeal and fish oil than the experimental diets. In Diet 2, 10% of the diet was replaced with BSFLM, resulting in 26.9% fish oil reduction. Diet 3 included both 10% BSFLM and 4.2% AO, leading to 46.3% fish oil reduction. Six hundred Chinook salmon were randomly distributed across 12 tanks, with each tank assigned to one of the three diets. The experiment spanned 52 weeks, allowing the fish to grow to near-market size. A 19-member sensory panel performed the evaluations of difference from control (DFC). Additionally, the physical properties of fillets were assessed, and nutrient compositions of diets and muscle tissues were analysed. Panellists reported several differences related to salmon colour, overall appearance and overall taste attributes in the fish fed the experimental diets. Specifically, the fish from the experimental diets exhibited weaker salmon colour and less overall taste. Physical-chemical analyses further reported differences among the diets: the fatty acid profiles in muscle tissues closely resembled those of their respective diets, and cooked muscle tissues from the Diet 3 were softer, corresponds to their lower shrinkage and higher moisture content. Results indicated the feasibility of the use of BSFLM and AO for partial replacement of fishmeal and fish oil. Exploring these alternative ingredients helps enhance aquafeed sustainability and meet the rising demand for aquaculture products.

Systematically Investigating the Qualities of Commercial Encapsulated and Industrial-Grade Bulk Fish Oils in the Chinese Market.

Fish oil is one of the most popular dietary nutritional supplements. Reports on the qualities of fish oils from Chinese markets are scarce, although the consumption of fish oil products in China is huge and increasing. This study systematically investigated the qualities of commercial encapsulated fish oils (CFs) and bulk fish oils (BFs) from Chinese markets, including oxidative level, sensory quality, color, metal element content, and unsaturated fatty acid content. Significant quality variations were observed both among individual CFs and between BFs: 65.2% of CFs (excluding one flavored sample) and one BF sample met China's Grade II fish oil oxidation product standards; 80.8% of CFs and three BFs were within regulatory limits for heavy metal contamination. A distinct fishy odor was detected in four CFs and one BF sample, while a pronounced rancid odor was observed in one CF sample. The EPA contents in 64% of CFs and DHA contents in 48% of CFs met their labeled claims. Furthermore, these five quality parameter categories demonstrated non-significant intercorrelations, with the fish oil unit price being independent of quality. These findings indicated that most BFs require refinement, and CFs require implementation of low-temperature dark storage/transportation protocols. This study provided comprehensive quality benchmarks for fish oil production and marketing.

Cracking the code of acrylamide and Nε-(carboxymethyl)lysine: Fish oil use and predictive strategies in potato chips during thermal processing.

Cracking the code of acrylamide and Nε-(carboxymethyl)lysine: Fish oil use and predictive strategies in potato chips during thermal processing.

Skin mucus and blood plasma as non-lethal sources of malnutrition protein biomarkers in meagre (Argyrosomus regius).

Skin mucus and blood plasma as non-lethal sources of malnutrition protein biomarkers in meagre (Argyrosomus regius).

Marine n-3 polyunsaturated fatty acids slow sleep impairment progression by regulating central circadian rhythms in type 2 diabetes.

Marine n-3 polyunsaturated fatty acids slow sleep impairment progression by regulating central circadian rhythms in type 2 diabetes.

Unlocking the release, digestion and absorption kinetics of DHA from different fish oil delivery systems: An in vitro and ex vivo study

Unlocking the release, digestion and absorption kinetics of DHA from different fish oil delivery systems: An in vitro and ex vivo study