PurposeThe purpose of this study is the design, fabrication and evaluation of a miniature ozone generator using the principle of electric discharge are presented.Design/methodology/approachThe device was fabricated using a low-temperature co-fired ceramics (LTCC) technology, by which a multilayered ceramic structure with integrated electrodes, buried channels and cavities in micro and millimeter scales was realized.FindingsThe developed ozone generator with the dimensions of 63.6 × 41.8 × 1.3 mm produces approximately 1 vol. % of ozone in oxygen flow of 15 ml/min, at an applied voltage of 7 kV.Originality/valueA miniature ozone generator, manufactured in LTCC technology, produces high amount of ozone and more than it is described in the available references or in datasheets of commercial devices of similar size.

PurposeThe purpose of this study is to design, fabricate and investigate low-temperature co-fired ceramic (LTCC) structures with integrated microfluidic elements. Special attention is paid to the study of fluid properties of micro-channels and microvalves, which are important constitutive parts of both, microfluidic systems and individual microfluidic devices.Design/methodology/approachSeveral test patterns of fluid channels with different geometry and different types of valves were designed and realized in LTCC technology. All test structures were tested under the flow of two fluids (liquids): water and isopropyl alcohol. Flow rates at different applied pressure were measured and hydrodynamic resistance and diode effect were calculated.FindingsThe investigation of the channels showed that viscosity of fluidic media has significant influence on the hydrodynamic resistance in channels with rectangular cross-section, while this effect is small on channels with square cross-section. The viscosity also has a decisive influence on the diode effect of different shape of valves, and therefore, it is important in the selection of the valve in practical applications.Research limitations/implicationsIn this work, the investigation of hydrodynamic resistance of channels and diode effect of passive valves is limited on selected geometry and only on two fluidic media and two applied pressures. All these and some other parameters have a significant influence on fluidic properties, but this will be the topic of the next research work, which will be supported by numerical modelling.Practical implicationsThe presented results are useful in the future designing process of LTCC-based microfluidic devices and systems.Originality/valueMicrofluidic in the LTCC structures is an unconventional use of this technology. Therefore, the fluid properties are relatively unsearched. On the other hand, the global use of microfluidic devices and systems is growing rapidly in various applications. They are mostly made by polymer materials, however, in more demanding applications; ceramic is a useful alternative.

Piezoelectric ceramic resonant pressure sensors have shown potential as sensing elements for harsh environments, such as elevated temperatures. For operating temperatures exceeding ~250 °C, conventional and widely used Pb(Zr,Ti)O3 (PZT) piezoelectrics should be replaced. Here, a ceramic pressure sensor from low-temperature co-fired ceramics (LTCC) was constructed by integrating a piezoelectric actuator made from bismuth ferrite (BiFeO3) on a diaphragm. This ferroelectric material was selected because of its high Curie temperature ( = 825 °C) and as a lead-free piezoelectric extensively investigated for high-temperature applications. In order to construct a sensor with suitable pressure sensitivity, numerical simulations were used to define the optimum construction dimensions. The functionality of the pressure sensor was tested up to 201 °C. The measurements confirmed a pressure sensitivity, i.e., resonance frequency shift of the sensor per unit of pressure, of −8.7 Hz/kPa up to 171 °C. It was suggested that the main reason for the hindered operation at the elevated temperatures could lie in the thermo-mechanical properties of the diaphragm and the adhesive bonding at the actuator-diaphragm interconnection.

PurposeIn this contribution, the design and integration of a piezoelectric vibrating device into low-temperature, co-fired ceramic (LTCC) structures are presented and discussed. The mechanical vibration of the diaphragm was stimulated with a piezoelectric actuator, which was integrated onto the diaphragm. Three different methods for the integration were designed, fabricated and evaluated.Design/methodology/approachThe vibrating devices were designed as an edge-clamped diaphragm with an integrated piezoelectric actuator at its centre, whose role is to stimulate the vibration of the diaphragm via the converse piezoelectric effect. The design and feasibility study of the vibrating devices was supported by analytical methods and finite-element analyses.FindingsThe benchmarking of the ceramic vibrating devices showed that the thick-film piezoelectric actuator responds weakly in comparison with both the bulk actuators. On the other hand, the thick-film actuator has the lowest dissipation factor and it generates the largest displacement of the diaphragm with the lowest driving voltage. The resonance frequency of the vibrating device with the thick-film actuator is the most sensitive for an applied load (i.e. mass or pressure).Research limitations/implicationsResearch activity includes the design and the fabrication of a piezoelectric vibrating device in the LTCC structure. The research work on the piezoelectric properties of integrated piezoelectric actuators was limited.Practical implicationsPiezoelectric vibrating devices were used as pressure sensors.Originality/valuePiezoelectric vibrating devices could be used not only for pressure sensors but also for other type of sensors and detectors and for microbalances.

We report results from an acute, single case study in the pig liver on the effects of a tissue ablation protocol (we named cryoelectrolysis) in which 10 min of cryosurgery, with a commercial cryosurgical probe, are delivered after 10 min of electrolysis generated by a current of about 60 mA. The histological appearance of tissue treated with cryoelectrolysis is compared with the appearance of tissue treated with 10 min of cryosurgery alone and with 10 min of electrolysis alone. Histology done after 3 h survival shows that the mixed rim of live and dead cells found around the ablated lesion in both cryosurgery and electrolytic ablation is replaced by a sharp margin between life and dead cells in cryoelectrolysis. The appearance of the dead cells in each, cryoelectrolysis, cryosurgery and electrolytic ablation is different. Obviously, this is an acute study and the results are only relevant to the conditions of this study. There is no doubt that additional acute and chronic studies are needed to strengthen and expand the findings of this study.

In this contribution the design and fabrication of ceramic microsystems with integrated different microfluidic elements and sensors will be presented. Ceramic microsystems are based on unconventional application of low-temperature co-fired ceramic technology and materials. This unconventional application is related to three-dimensional ceramic structures, such as cantilevers, ledges, bridges, diaphragms, valleys, channels, holes and cavities, valves, mixers, diffusors, distributors, collectors, flow limiters, sensors, and actuators.

An exploratory study of the impact of housing on the characteristics of a low-temperature co-fired ceramic (LTCC) pressure sensor is presented. The ceramic sensor structure is sealed in a plastic housing. This may have non-negligible effect on the final characteristics and should be considered in the early design phase. The manufacturability issue mainly concerning the selection of available housing and the most appropriate materials was considered with respect to different requirements for low and high pressure ranges of operation. Numerical predictions showed the trends and helped reveal the critical design parameters. Proper selection of the adhesive material remains an essential issue. Curing of the epoxy adhesive may introduce non-negligible residual stresses, which considerably influence the sensor’s characteristics.

A miniature methanol reformer system has been designed and built to technology readiness level exceeding a laboratory prototype. It is intended to feed fuel cells with electric power up to 100 W and contains a complete setup of the technological elements: catalytic reforming and PROX reactors, a combustor, evaporators, actuation and sensing elements, and a control unit. The system is engineered not only for performance and quality of the reformate, but also for its lightweight and compact design, seamless integration of elements, low internal electric consumption, and safety. In the paper, the design of the system is presented by focussing on its miniaturisation, integration, and process control.

Methanol decomposition on Pt/CeO2/ZrO2 catalyst is studied inside a packed bed microreactor in the temperature range of 300–380 °C. The microreactor is fabricated using low-temperature co-fired ceramic (LTCC) technology, which is well suited for the production of relatively complex three-dimensional structures. It is packed with 2 wt% Pt–CeO2 catalyst, which is deposited onto ZrO2 spherical particles. A 1D mathematical model, which incorporates diffusion, convection and mass transfer through the boundary layer to the catalyst particles, as well as a 3D computational fluid dynamics model, are developed to describe the methanol decomposition process inside the packed bed. The microreactor exhibits reliable operation and no catalyst deactivation was observed during three months of experimentation. A comparison between the 1D mathematical model and the 3D model, considering the full 3D geometry of the microreactor is made and the differences between the models are identified and evaluated.

In this paper we present the results of an investigation of the long-term stability of piezoresistive LTCC-based pressure sensors with the main emphasis on the effects of accelerated ageing. Noise spectroscopy was considered as a possible method for predicting the stability of the sensors’ characteristics. The experiments showed that the stability of the sensors’ offset voltage clearly relates to the low-frequency noise of the output signal: a lower noise level corresponds to a better long-term stability. An additional important finding is that the accelerated ageing that was carried out through the pressure cycling does not cause any significant increase in the sensors’ signal noise. This result suggests that the performed pressure loadings do not introduce some critical cracks in the thick-film sensing resistors, which may adversely influence the sensors’ stability. Moreover, the experiments revealed that the poor stability of the sensors, which was manifested in noticeable changes in the offset voltage and the sensitivity of some sensors after the overload pressure cycles, comes from defects that are not detectable using typical characterisation measurements and long-term stability tests. Since the unstable sensors always have a higher low-frequency noise of the output voltage in comparison with the stable sensors, the noise measurements can be described as a successful pre-screening test for a relatively quick assessment of the sensors’ long-term stability.