Considering the urgent circumstances of a Modernity in crisis, this paper seeks to identify the paradigms of a political epistemology that would encompass a project to overcome it, known as Postmodernism. To this end, it employs a historical conceptual method that analyzes, first, the emergence of modern political epistemology, particularly the critical contributions of Machiavelli and Nietzsche. Secondly, it analyzes the epistemological contradictions of the modern world and their consequent possibility of being overcome under the postmodern project. Critically, it emonstrates that the modern dynamic is unsustainable and that the ethical-political pursuit of justice is the primary basis of the postmodern epistemological turn, seeking to restore human freedom reconnected with its sense of responsibility