Chemotherapy-induced peripheral neuropathy (CIPN)-related pain seriously affects patients' quality of life (QoL). Previous studies have shown that exercise interventions can improve symptoms such as pain in patients with CIPN. However, the optimal exercise intervention remains unknown. To explore the comparative effects and ranks of all exercise-based interventions in improving CIPN-related pain, CIPN symptoms, and QoL in cancer patients experiencing CIPN. We searched 10 electronic databases to identify randomized controlled trials from their inception up to June 23, 2024. We used Review Manager 5.4.1 and Stata v14.0 for traditional meta-analysis and network meta-analysis (NMA). This review included 14 randomized controlled trials with a total of 1127 participants. The NMA revealed that: (a) a combination of strengthening, stretching, and balance exercises (standardized mean difference [SMD] = -11.43, 95% confidence interval [CI], -13.60 to -9.26) was the most effective intervention for improving CIPN-related pain; (b) walking exercise (SMD = -2.07, 95% CI, -2.70 to -1.43) yielded better outcomes in alleviating CIPN symptoms; and (c) interventions focused on muscle strengthening and balancing exercises (SMD = 1.03, 95% CI, 0.40 to 1.65) were most effective for improving QoL. Our NMA indicated that strengthening, stretching, and balance exercises could potentially benefit the improvement of CIPN-related pain. Further evidence is needed. This study provides evidence about the effectiveness of exercise interventions for CIPN-related pain. Future research on pain management in subgroups of CIPN patients may benefit from exploring the exercise strategies identified in this study, providing important support to healthcare professionals.

Postoperative pharyngeal pain is common in patients with thyroid cancer undergoing day-case surgery, with approximately 60%-90% affected. Wrist-ankle acupuncture (WAA) offers a potential alternative but lacks clinical validation in day surgery settings. This study aimed to assess the effectiveness and safety of WAA in reducing postoperative pharyngeal pain in patients with thyroid cancer undergoing day-case surgery. Seventy-two patients undergoing thyroidectomy were randomized into the WAA experimental group (n = 36) or the control group (n = 36). The WAA experimental group received standardized care plus subcutaneous needle insertion at wrist points (Upper 1 and Upper 6) postoperatively, whereas the control group received standard care alone. Pain was assessed using the visual analog scale at 3, 4, 9, and 27 hours, and predischarge. Secondary outcomes included the Houston Pain Outcome Instrument and the 15-item Quality of Recovery scale. At 9 and 27 hours post surgery, the experimental group reported significantly lower pain scores (P < .001); satisfaction with pain control was also significantly higher (P < .001). The WAA group had minor adverse events and no serious complications. Additionally, the experimental group experienced better postoperative sleep and overall health (P < .05). Wrist-ankle acupuncture significantly relieves postoperative sore throat in patients with thyroid cancer during day surgery. This work establishes a foundation for integrating WAA into modern surgical recovery pathways. However, larger randomized controlled trials are needed to determine effectiveness across different institutions and populations. Wrist-ankle acupuncture offers a nonpharmacological alternative for pain management in thyroid cancer surgery. Further studies are needed to confirm its broader applicability and effectiveness in diverse patient populations.

Symptom management guidelines are primarily written for single cancer symptoms despite patients experiencing multiple co-occurring symptoms. Coordinating recommendations across guidelines based on patients' self-report of symptom clusters may facilitate efficient multisymptom self-management. The aim of this study was to evaluate the feasibility of a nurse-coordinated approach to multisymptom management among patients receiving chemotherapy. Forty-one adults receiving cancer chemotherapy and experiencing ≥2 symptoms were recruited to this pilot randomized controlled trial. Participants self-reported symptom cluster experiences weekly, over 2 cycles of chemotherapy. All participants received usual care during the first cycle on study, and half were randomized to enhanced care during the second cycle. A nurse interventionist reviewed participants' symptom cluster self-reports to understand symptom relationships and etiology, selected 1 or more guideline-based self-management strategies to treat multiple symptoms, and provided participants with weekly self-management instructions. Recruitment (85%) and retention (83%) met feasibility criteria. Nurse interventionists successfully coordinated a treatment plan with fewer self-management strategies than symptoms for 84% of participants' symptom cluster reports. Coordination challenges included complex multisymptom etiology, prioritizing among self-management strategies, and symptoms with no guideline-recommended treatments. Most participants (≥72%) reported satisfaction with the intervention and study procedures. Nurse coordination of management strategies for clustered symptoms is feasible and acceptable, and merits further intervention development. Eliciting patients' self-reports of symptom clusters provides important insights to drive management recommendations. Drawing on this knowledge and using evidence-based guidelines, oncology nurses may identify self-management strategies that are effective across multiple co-occurring symptoms to reduce patients' symptom and self-management burden.

Induction chemotherapy not only can effectively reduce tumor load and improve disease symptoms in patients with multiple myeloma (MM) but can also lead to toxic side effects, which increase symptom burden. Cross-lagged panel network analysis provides a novel insight into symptom influence mechanisms during multiple time periods. The aims of this study were to analyze the complexity and dynamic changes of symptoms experienced by patients newly diagnosed with MM in relation to the courses of chemotherapy and provide evidence for effective and precise symptom management. A total of 175 patients newly diagnosed with MM were selected to complete the Memorial Symptom Assessment Scale-Chinese version at baseline and the first 4 courses of chemotherapy. Exploratory factor analysis was used to extract symptom clusters. Cross-lagged panel networks were constructed to identify crucial nodes in the network and explore predictive and interactive effects among symptoms. Four symptom clusters were extracted: psychological distress, disease behavior, fatigue-lack of appetite, and abdominal distension-constipation. During T0 → T1, "feeling irritable" exhibited the highest out-EI (outgoing expected influence), predicting T1 "difficulty falling asleep" and "nausea." During T1 → T2 and T2 → T3, "weight loss" predicted T2 "lack of energy" and "loss of appetite," and predicted T3 "worry," "feeling nervous," and "feeling irritable," respectively. During T3 → T4, "feeling nervous" predicted "pain," "loss of appetite," and "lack of energy" during T4. "Tension" and "irritability" in the psychological symptom cluster and "weight loss" in the fatigue-related symptom cluster were "high output centrality symptoms" predicting other symptoms and the dynamic change of the whole network. Our findings provide a theoretical intervention target for nursing intervention with patients with MM.

Breast cancer is a leading cause of cancer-related morbidity and mortality and imposes substantial financial strain on individuals and society. Minoritized groups, particularly Black/African American (AA) women, face a heightened risk of financial toxicity during treatment, even after accounting for socioeconomic differences. The aim of this study was to explore and provide meaningful interpretations of the financial experiences of Black/AA breast cancer survivors (BCSs). We conducted a systematic search to synthesize qualitative studies, published from 2009 to 2024, on the financial experiences of Black/AA BCSs during treatment. The Meta-Ethnography Reporting Guidance was used to follow Noblit and Hare's 7 phases of meta-ethnography. Quality assessment of the studies was done using the Joanna Briggs Institute critical appraisal tool. Five studies involving 135 participants (102 Black women), aged 28 to 80 years, were analyzed. Five themes were formed: (1) insurance/systemic gatekeeping and the conditionality of care, (2) psychological stress, (3) reduced adherence and possible missed appointments, (4) from bills to barriers, and (5) coping strategies to manage financial burden. This review highlights substantial financial challenges faced by Black/AA BCSs, extending beyond medical expenses, affecting treatment adherence, psychological well-being, and long-term quality of life. Oncology nurses play a critical role in reducing financial disparities by screening for financial distress, providing referrals, and delivering culturally sensitive care. Nurse and peer navigation programs, although not universally accessible, show promise in mitigating financial hardship and improving adherence and survivorship outcomes. Expanding such programs into survivorship care planning is essential to advancing equity in oncology.

Postsurgery physical activity is crucial for lung cancer rehabilitation. However, patients often lack sufficient activity at home, and the types of activities they engage in have not been well studied in China. This study aimed to identify physical activity profiles and assess their relationship with demographic and clinical characteristics, postoperative symptoms, and health capabilities in Chinese patients with lung cancer post surgery at home. A total of 370 home-based patients who had undergone lung cancer surgery 1 month prior participated. The MD Anderson Symptom Inventory, the Self-Rated Abilities for Health Practices Scale, and the International Physical Activity Questionnaire were used. A latent profile analysis was conducted to examine the energy expenditure of various types of physical activity. Influencing factors of various activity profiles were identified using univariate and multivariate logistic regression analyses. Three latent categories were identified. Patients presenting discomfort symptoms a month after surgery displayed a heightened propensity to embrace household-oriented physical activities. In comparison, younger patients engaged in more occupation-oriented physical activities. Patients who achieved elevated scores on the Self-Rated Abilities for Health Practices Scale tended to engage in more exercise routines. The physical activity of home-based patients 1 month after lung cancer surgery was generally a medium or low level. Age, postoperative symptoms, and self-rated health status can be used to identify the types of physical activity of these patients. Healthcare providers should actively monitor patients with postoperative symptoms and low self-assessed health, and tailor home-based physical activity recommendations to suit specific age groups.