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A STUDY ON WOMEN ATTENDING GYNAECOLOGY OUTPATIENT DEPARTMENT UNDERGOING PAP SMEAR EXAMINATION AND FOLLOW-UP OF ABNORMAL PAP SMEAR USING COLPOSCOPY

Cervical cancer is the fourth most common cancer in women. In 2018, an estimated 570,000 women were diagnosed with cervical cancer worldwide and about 311,000 women died from the disease. It is the most common genital cancer among women in India. Pap smear is very useful in detecting abnormal cells and colposcopy locates the abnormal lesion when pap smear is abnormal. The objective of the study is to evaluate the women coming to the Gynaecology Outpatient Department undergoing pap smear and follow-up of abnormal smear using colposcopy. 103 women in the age group of 26-75(50.29+2.56) years who attended the gynecology outpatient department (GOPD)at a tertiary care teaching hospital in central Kerala with various clinical symptoms were screened by pap smear testing over two weeks. The smear was obtained using an Ayre spatula and it was spread over a glass slide which was placed in 95% ethyl alcohol in a coplin Jar. It was then sent to the department of pathology for cytopathological examination followed up using colposcopy and biopsy was done in the cases with abnormal colposcopy. Among these women,46.6 percentage have a normal pap smear 47.6% have an abnormal smear, and 5. 8 % have an atrophic smear. Among abnormal smear 4.8% are ASCUS, 1.9% LSIL, 0.97% SCC, 0.97% high-grade adenocarcinoma, and 37.86% inflammatory smears. As per International guidelines, women with abnormal pap smear tests should undergo colposcopy and those with abnormal colposcopy findings should undergo biopsy. Awareness about cancer should be increased and women should be motivated to undergo screening.

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Geospatial Modeling of the Nitrate Distribution as an Indicator of Aquatic Fertility in the Lagoon Waters of the Mangrove Information Center (PIM), Pekalongan

In the lagoon area of the Mangrove Information Center (PIM), Pekalongan, annual flooding leads to inundation in some land areas, particularly pond areas, lagoons, and residential areas. The area of submergence due to tidal floods in 2020 reached 783.99 hectares. The construction of embankments to the south of the lagoon as protection against flooding has transformed the northern area into a lagoon. Our research, crucial for understanding and managing these environmental changes, aims to determine and analyze the content and distribution of nitrate in the Lagoon Area of Mangrove Information Center Waters, Pekalongan. This was achieved through a thorough process of in situ observations based on purposive sampling at six sampling sites on June 22, 2023. The nitrate distribution data was then interpolated with a 2D current hydrodynamic model, ensuring the most accurate representation of the data. The value of nitrate content in the Mangrove Information Center lagoon ranges between 0.0065-0.1072 mg/L. This distribution pattern, influenced by deposits of mangrove litter, the depth of the lagoon, and water circulation, reflects the accumulation of physical and chemical influences in the waters.

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