The high sensitivity of the spectrum and wave functions to boundary conditions, termed the non-Hermitian skin effect, represents a fundamental aspect of non-Hermitian systems. While it endows non-Hermitian systems with unprecedented physical properties, it presents notable obstacles in grasping universal properties that are robust against microscopic details and boundary conditions. In this Letter, we introduce a pivotal theorem: in the thermodynamic limit, for any non-Hermitian systems with finite-range interactions, all spectral moments are invariant quantities, independent of boundary conditions, posing strong constraints on the spectrum. Utilizing this invariance, we propose a new criterion for bulk dynamical phases based on experimentally observable features and applicable to any dimensions and any boundary conditions. Based on this criterion, we define the bulk dispersive-to-proliferative phase transition, which is distinct from the real-to-complex spectral transition and contrasts with the traditional expectation that the existence of eigenvalues above the real axis implies proliferative behavior. We verify these findings in 1D and 2D lattice models.
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