In this paper, we study congruence of curves in Weyl-Otsuki spaces using the Ricci's coefficients of that congruence in orthogonal case. We first prove that the Ricci’s coefficients determine the regular general connection of an Otsuki space. Then we give the condition for these coefficients in Weyl-Otsuki spaces to be skew-symmetric in the first two indices as in Riemannian spaces. We obtain the necessary and sufficient conditions for the curves of a congruence to be geodesic, normal and irrotational, respectively. Finally, we prove that if a congruence satisfy the equation, and any two of the conditions that to be geodesic, normal and irrotational, then it also satisfies the other third one.

ADAMTS-3 is a procollagen amino proteinase mainly expressed in type II collagen-rich tissues and its primary function is to maturate amino ends of the type II collagen precursors. This maturation process allows correct fibril formation. ADAMTS-3 also has a tumor-suppressive function by regulating the fibronectin expression in the ECM. C/EBPα is a transcription factor playing a pivotal role in the cell cycle regulation. Dysregulations in the C/EBPα expression have been reported in solid tumors. C/EBPα expression has been identified to be associated with the metabolism and prognosis of a malignant bone tumor, osteosarcoma (OS). High heterogeneity, metastasis capability, and recurrence lead to poor prognosis and survival rates in OS. Multiple genetic and epigenetic factors affect OS development. Alterations in the ECM elements are closely related to OS development and progression. According to the in-silico analyses, the ADAMTS-3 promoter includes multiple C/EBPα binding sites suggesting that C/EBPα could have a regulatory effect on ADAMTS-3 transcriptional regulation. In the present study, over-expression of the C/EBPα decreased ADAMTS-3 mRNA and protein levels in Saos-2 and MG-63 osteosarcoma models. Ectopic expression of the C/EBPα also led to alterations in some fibrillar collagen expression levels. Enhanced C/EBPα levels resulted in an increase in the type I and II collagen expression levels but didn’t change the type III collagen expression level in Saos-2 cells.

In this paper, some equalities and inequalities involving the Riemannian curvature invariants are obtained on 3-semi slant submanifolds of cosymplectic 3-space forms. Obtained relations for 3-semi slant submanifolds are examined on 3-slant, invariant and totally real submanifolds.

Multi-functional FeCo nanoparticles (NPs) exhibit unique structural, magnetic and catalytic properties, making them versatile materials with potential applications in diverse fields. In this work, we investigated the structural, electrochemical and magnetic properties of as-prepared FeCo NPs synthesis by polyol method. X-ray diffraction analysis revealed multiphase structures: FeCo and α-Fe2O3 phases and scanning electron microscopy images confirmed spherical-like structures of FeCo NPs with an average size of 12.4 ± 0.1 nm. The electrochemical properties of FeCo NPs were investigated using a three-electrode setup in a 1 M KOH electrolyte at room temperature. The onset potentials for FeCo catalysts were found to be -0.15 V for ORR, 0.25 V for OER, and -1.26 V for HER. Tafel measurements further elucidated the reaction mechanism, revealing corrosion potentials of -0.165 V for ORR and 0.215 V for OER, with Tafel slopes of 228 mV dec-1 and 48 mV dec-1, respectively. A significant increase in magnetization was observed below 25 K in both zero-field-cooled and field-cooled curves, with a magnetic transition occurring at Ts=15 K, possibly indicating a ferromagnetic-to-antiferromagnetic phase transition. The hysteresis loop measurements revealed coercive field values ranging from 968 Oe at 5 K to approximately 206 Oe at 320 K, indicating a relaxation in magnetic spin orientation with increasing temperature. The saturation magnetization (Ms) values were recorded as 15.2 emu/g under a 5 T magnetic field, and the remanent magnetization (Mr) showed dominant ferromagnetic properties at 5 K with an Mr/Ms ratio indicating soft magnetic behavior. The magnetic susceptibility of FeCo NP exhibited a peak at approximately 25 K, and the Curie-Weiss law provided an estimated θ angle of -9.58°, suggesting antiferromagnetic interactions.

In this research study, we aim to approximate a solution for the mathematical model of the Human Immunodeficiency Virus (HIV) infection of CD4+T-cells. An operational matrix method based on Chebyshev orthogonal polynomials has been adapted to obtain numerical solutions for the model of HIV infection of CD4+T-cells. The proposed numerical scheme is built on a system of a nonlinear algebraic equation, including coefficients of a finite Chebyshev series that are represented the approximate solutions of the model. Results are compared to existing methods to verify the accuracy of the numerical scheme.

A total of 10 actinobacterial strains were isolated from a lichen and an orchid species by employing a selective isolation procedure for actinobacteria. Antimicrobial activities of the isolates were evaluated against Aspergillus niger ATCC 16404, Candida albicans ATCC 10231, Enterococcus faecalis ATCC 29212, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 700603, Pseudomonas aeroginosa ATCC 27853, Salmonella enterica ATCC 13311, Staphylococcus aureus ATCC 29213 and Listeria monocytogenes NCTC 5348. Out of the 10 isolates, eight showed antimicrobial activity against at least one pathogen. For molecular identification of the strains, 16S rRNA gene sequence analysis was performed. The pairwise comparison of the 16S rRNA gene sequences of the strains with the databases showed that the strains are members of the genus Streptomyces by sharing 98.9 – 100% gene sequence similarities. Phylogenetic relationships of the strains within the genus Streptomyces were revealed by maximum likelihood and maximum parsimony phylogenetic trees. The results revealed that unexplored environmental habitats like lichens and plant tissues may represent a potential reservoir for novel actinobacteria with promising bioactivity features.

La2NiMnO6 çift-katlı perovskit manganit sistemi sol-jel yöntemi ile üretilmiş, LNM-1000 örneği 1000 ˚C'de, LNM-1100 örneği ise 1100 ˚C'de sinterlenmiştir. Üretilen örneklerin yapısal, morfolojik, manyetik ve manyetokalorik özellikleri incelenmiştir. Numunelerin kristal yapısının Rombohedral yapıda ve R3 ̅c uzay grubunda olduğu belirlendi. Morfolojik özellikleri incelendiğinde LNM-1000 numunesinin küçük yapılı, çok köşeli ve düzensiz şekilli taneler içerdiği, LNM-1100 numunesi içinse bu bilgilerin yanında bazı yerlerde tane sınırlarının belirsizleştiği görülmektedir. LNM-1000 ve LNM-1100 numuneleri için Curie sıcaklıkları 200 ve 220 K olarak belirlenirken efektif manyetik moment değerleri sırasıyla 1.75 ve 2.13 B olarak hesaplanmıştır. Arrot grafikleri, numunelerin ikinci dereceden manyetik faz geçişi sergilediğini göstermektedir. Maksimum manyetik entropi değişimi ve bağıl soğutma gücü değerleri LNM-1000 ve LNM-1100 numuneleri için sırasıyla 0,21, 0,25 J kg-1 K-1 ve 46,2, 50,5 J kg-1 olarak hesaplanmıştır. Örnekler Gd2NiMnO6 örneğinden (5 K) çok daha yüksek olan oda altı sıcaklık aralığında Curie sıcaklığına ve ikinci dereceden manyetik faz geçişine sahip olmalarına rağmen, nispeten düşük manyetik entropi değişim değerleri, manyetik soğutucu malzeme olarak kullanımlarını sınırlandırmaktadır.