Tax compliance significantly impacts tax revenue, with increased compliance correlating to heightened state revenue. This study investigates the influence of taxpayer awareness, taxation understanding, tax sanctions, and tax service quality on tax compliance among motor vehicle taxpayers at the Sidoarjo Samsat Office. The research employs a quantitative descriptive approach, utilizing primary data gathered through questionnaires. The population consists of 955,635 registered taxpayers, with 100 selected through incidental sampling. Findings reveal that taxpayer awareness, taxation understanding, tax sanctions, and service quality positively influence tax compliance. This study addresses a gap in understanding taxpayer behavior and provides insights for policymakers to enhance compliance strategies, thereby optimizing tax revenue. Highlight: Descriptive quantitative approach: Primary data collected via questionnaires. Key findings: Factors affecting tax compliance elucidated. Policy insights: Informing strategies for enhancing tax compliance and revenue. Keywoard: Tax compliance, Awareness, Understanding, Sanctions, Service quality.

Most of the existing recommendation models are designed based on the principles of learning and matching: by learning the user and item embeddings and using learned or designed functions as matching models, they try to explore the similarity pattern between users and items for recommendation. However, recommendation is not only a perceptual matching task, but also a cognitive reasoning task because user behaviors are not merely based on item similarity but also based on users’ careful reasoning about what they need and what they want.

Objective: The objective of this in-vitro study was to explore the pro-apoptotic potential of eugenol (4-allyl-2-methoxyphenol) on Human Leukemia-60 (HL-60) cell line as a potent phytochemical in intensive care setting to leukemia patients. Methodology: After formal approval by all of the respective ethical committees, this study was simultaneously conducted at all respective institutional departments. The study included culturing HL-60 cell line and its treatment with serial concentrations of eugenol for calculation of subsequent IC50 values (half-maximal inhibitory concentration) via MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay, expression analysis of gene, comparative analysis of relative gene fold (Intrinsic Biomarkers Caspase-3, Caspase-9) as apoptosis mediator markers followed by RT-qPCR. Cellular apoptotic morphology was confirmed via Hoechst 333258 staining. Results: For HL-60 cell line, the IC50 of eugenol (14.1 uM) showed high gene expression of pro-apoptotic biomarkers (Caspase-3 and Caspase-9). Hoechst 333258 staining showed prominent apoptotic bodies leading to nuclear fragmentations. Conclusion: Eugenol proved to possess robust pro-apoptotic potential leading to diagnostic efficacy against leukemia HL-60 cell line. Further studies would help in identifying key mechanisms by which eugenol exhibits anti-cancer potential against HL-60 cell lines. Abbreviations: HL-60 - Human Leukemia-60; IC50 - Half-Maximal Inhibitory Concentration Keywords: Eugenol, Pro-apoptotic Effects, Intensive Care, Anti-Cancer Mechanisms, HL-60, Natural Chemotherapeutics Citation: Khaliq HMH, Bughio R, Nangdev P, Aziz O, Javed W. Integrating eugenol with intensive care in leukemia patients: exploration of pro-apoptotic potential against HL-60, human leukemia cell line. Anaesth. pain intensive care 2024;28(5):871−875; DOI: 10.35975/apic.v28i5.2491 Received: June 18, 2024; Reviewed: August 03, 2024; Accepted: August 11, 2024

Este texto aborda as orquestras como bem cultural, focando especialmente o papel e significância das orquestras comunitárias no ensino coletivo de música. Tais grupos têm como foco a integração social e o fortalecimento identitário pela linguagem musical, a partir de fenômenos sociais desencadeados pela promoção de vivências culturais e educativas. A discussão é um recorte de uma pesquisa de doutorado em andamento e abrange o estado de ativação desse patrimônio. O objetivo é articular aplicações de saberes do campo da educação patrimonial em processos e práticas de políticas públicas para a cultura e para a cidadania, cujas bases são as orquestras. Após uma breve introdução ao contexto, apresenta-se uma discussão preliminar e considerações sobre as informações coletadas até o momento.

This research investigates the influence of Brand Image, Price, and Promotion on Purchase Decisions for Gamis Pelangi Hijab in Driyorejo, employing a descriptive quantitative approach. Utilizing multiple linear regression analysis on data collected from 96 respondents via purposive sampling, the study reveals significant effects: (1) Brand Image positively influences purchasing decisions; (2) Price has a significant impact on purchasing choices; (3) Promotional activities affect purchase decisions. Through regression analysis using SPSS 22, the study elucidates the pivotal role of these factors in consumer behavior, providing insights for marketers aiming to enhance consumer engagement and strategic marketing initiatives in the modest fashion industry. Highlight: Quantitative analysis of purchase decisions for modest fashion. Sample selection based on non-probability purposive sampling technique. Multiple linear regression analysis conducted using SPSS version 22. Keywoard: Gamis Pelangi Hijab, Purchase Decisions, Brand Image, Price, Promotion

This research aims to analyze and describe the strategies implemented by BUMDES Sumber Lestari in developing the Sumber Dhuwur tourist attraction. Tourism development significantly influences regional and citizen income, job creation, and economic activities. Utilizing qualitative methods, data were collected through interviews with village officials, the BUMDES chairman, local residents, and visitors, along with observations and documentation. The study uses qualitative descriptive analysis, involving data reduction, presentation, and conclusion drawing. Results indicate that BUMDES Sumber Lestari has effectively focused on infrastructure and facility development, but has yet to optimize human resource management in tourism and the creative economy. The research provides insights into strategic planning for rural tourism development, emphasizing the need for comprehensive human resource strategies to enhance competitiveness and economic impact. Highlight: Effective infrastructure and facility development by BUMDES Sumber Lestari. Human resource management needs optimization in tourism. Strategies enhance income and job creation. Keywoard: Tourism Development, BUMDES Strategy, Infrastructure, Human Resources, Economic Impact

Background: Foreign bodies are frequently encountered in the field of otolaryngology, specifically within the domains of the ear, nose, and throat (ENT). Serious complications, such as tympanic perforations and bronchoaspiration, are infrequently observed. Objective: To see the common site of impactions and complications associated with Foreign Bodies in the UADT. Methods: The Department of Otolaryngorhinology and Head-Neck Surgery at Dhaka Medical College Hospital conducted a cross-sectional study inside a hospital setting. The study was conducted from March 23, 2019, to September 22, 2019. The study included individuals who had a prior medical record of either inhaling or being impacted by a foreign object, as well as individuals who had a history of difficulty swallowing. Results: In this study, the majority of patients (70.0%) were found to be within the age range of 0 to 10 years. The average age of the patients was 6.1±2.8 years. This study found that foreign bodies were frequently observed to be impacted in the nose (42%), oesophagus (20%), and throat (38.0%).There are three main categories of foreign bodies: metallic foreign bodies, which account for 36.0% of cases, non-metallic foreign bodies, which account for 44.0% of cases, and living foreign bodies, which account for 20.0% of cases. The present study has provided evidence that non-invasive treatment methods, specifically direct vision only, accounted for the majority (42.0%) of the treatment approaches utilized. Laryngoscopy was deemed necessary in 38.0% of the patients, whereas esophagoscopy was performed in 14.0% of the cases. The present investigation involved the performance of endoscopic removal of foreign bodies (FB) in 6.0% of cases. Within the scope of this inquiry, it was noted that three subjects experienced postoperative challenges, encompassing sensations of discomfort, instances of bleeding, and issues associated with anesthesia. Conclusion: The majority of instances involving foreign .....

This study evaluates bankruptcy potential in food and beverage companies listed on the Indonesia Stock Exchange during 2018-2022 using four methods: Grover, Springate, Zmijewski, and Altman. Analyzing data from 31 sampled companies, the research employs descriptive quantitative methods and SPSS 26 analysis. Findings reveal varied bankruptcy predictions: Grover predicts 3 potential bankruptcies, Springate identifies 18, Zmijewski finds none, and Altman predicts 14. Notably, Zmijewski's method demonstrates superior accuracy. These results aid investors in understanding company performance and inform future financial strategies, addressing a critical need in early bankruptcy prediction for the food and beverage industry. Future research may explore additional prediction models and extend the study period to enhance predictive accuracy further. Highlight: Diverse methods: Grover, Springate, Zmijewski, Altman offer varied bankruptcy predictions. Zmijewski's accuracy: Highest accuracy among methods for bankruptcy prediction. Investor insight: Guides future financial decisions based on company performance analysis. Keywoard: Bankruptcy, Food & beverage, Stock Exchange, Analysis, Prediction.