Western Medicine Treatment Research Articles

Research Progress of Chinese and Western Medicine in Treatment of Rheumatoid Arthritis

At present, the etiology of rheumatoid arthritis (RA) is not clear, and its pathogenesis has not been clarified. For this, in clinic can only make corresponding treatment for the onset period and sequelae of the disease. Through reviewing relevant literature in recent years, it is found that the combined use of traditional Chinese and western medicine has great advantages in the treatment of rheumatoid arthritis. This paper will analyze and summarize the current treatment status and medication rules of traditional Chinese and western medicine for rheumatoid arthritis, hoping to provide reference for clinical treatment plans, so as to further improve clinical efficacy and improve treatment plans.

Research Progress on the Pathogenesis of Colorectal Cancer and Integrated Traditional Chinese and Western Medicine Treatment

Research Progress on the Pathogenesis of Colorectal Cancer and Integrated Traditional Chinese and Western Medicine Treatment

The Influence of Integrated Chinese and Western Medicine Treatment on the Quality of Life and Laboratory Indicators of Patients with Novel Coronavirus Pneumonia

The Influence of Integrated Chinese and Western Medicine Treatment on the Quality of Life and Laboratory Indicators of Patients with Novel Coronavirus Pneumonia

Overview of Radiation Enteritis and Progress in Treatment of Traditional Chinese and Western Medicine

Overview of Radiation Enteritis and Progress in Treatment of Traditional Chinese and Western Medicine

Research progress of CHD combined with anxiety and depression in Chinese and Western medicine

Coronary atherosclerotic heart disease (CHD) is one of the common diseases of the cardiovascular system, and it is also a common disease that seriously endangers human health. Patients with CHD are usually combined with anxiety and depression. In recent years, a large number of studies have shown that the incidence of CHD combined with anxiety and depression is gradually increasing, which seriously affects the prognosis of the disease and the quality of life of patients. This article reviews the epidemiology, pathogenesis and treatment of traditional Chinese and Western medicine, and provides reference for clinical practice.

Research Progress on the Combination of Acupuncture and Medicine in the Treatment of Premature Ovarian Failure

Premature ovarian failure (POF) is a condition in which the ovarian reserve function decreases due to a variety of factors, resulting in menstrual irregularities, amenorrhea, and decreased fertility before the age of 40. POF is a common reproductive endocrine disorder in gynecology that seriously affects the physical and mental health of women of appropriate age. Western medicine mostly uses hormone replacement and assisted reproduction techniques in clinical treatment, but in the long run, the side effects are large. With the development of Chinese medicine in recent years, the efficacy of Chinese medicine in the treatment of POF has been recognized. A large number of studies have shown that the combined effect of Chinese and Western medicine in the treatment of POF is better than that of Chinese medicine alone. The treatment methods mainly include Chinese medicine combined with Western medicine therapy, Chinese medicine combined with acupuncture therapy, Western medicine combined with acupuncture therapy treatment and Chinese medicine - Western medicine - acupuncture triple therapy. It is found that the combined effect of Chinese and Western medicine is better than the treatment of Chinese medicine or Western medicine alone, with significant clinical effect, which can effectively improve the endocrine level of the body, restore normal menstruation and improve fertility.

Research Progress on the Formation Mechanism of Renal Fibrosis and the Treatment of Chinese and Western Medicine

Research Progress on the Formation Mechanism of Renal Fibrosis and the Treatment of Chinese and Western Medicine

Progress in Traditional Chinese and Western Medicine Diagnosis and Treatment of Bronchial Asthma

Progress in Traditional Chinese and Western Medicine Diagnosis and Treatment of Bronchial Asthma

Effect and mechanism of Yupingfeng Powder on preventing recurrent respiratory tract infection in children with refractory nephrotic syndrome

Primary nephrotic syndrome in children is a group of clinical syndromes caused by the significant increase in the permeability of glomerular filtration membrane to plasma albumin and the loss of a large amount of albumin from urine due to various reasons. It is sensitive to hormones but easy to relapse, and may be dependent on hormones or resistant to drugs after repeated attacks, thus affecting the prognosis. Clinically, it is summarized as refractory nephrotic syndrome in children. Respiratory tract infection is one of the main factors causing the recurrence of refractory nephrotic syndrome in children. Yupingfeng Powder is the prescription of fuzheng Gubenjing, simple and effective, and it is widely used in clinic. Modern research confirmed that Yupingfeng can promote immunoglobulin IgA, IgG, IgE and monocyte macrophages, improve the immune function of the body, in recent years YuPingFeng alone or combined western medicine treatment of children repeated respiratory tract infection shows a unique curative effect and advantages, thus reducing the recurrence frequency of pediatric refractory nephrotic syndrome and frequency.

Research Progress of Traditional Chinese Medicine in the Treatment of Post-Stroke Depression

Stroke is one of the public health problems widely concerned by many countries in the modern world. It is a kind of cerebrovascular disease with high risk. Most patients will have sequelae after stroke, such as hemiplegia, speech impairment, limited walking, etc. Depression is also one of the common sequelae. Patients are mainly characterized by low mood, unwilling to communicate with others, insomnia, and even negative thoughts of suicide. Post-stroke depression has adverse effects on patients and society, which greatly affects the normal life and work of patients and affects social stability. Western medicine treatment of post-stroke depression is mainly based on oral drugs, but it will bring many adverse reactions, such as drug resistance, dependence, and drug toxicity. Long-term medication treatment brings certain economic pressure. Traditional Chinese medicine (TCM) is a medicine with rich experience accumulated for a long time in China. It has a positive effect on the treatment of stroke and post-stroke depression. It has the characteristics of simplicity, low price and low toxicity, and is widely accepted by society and patients. There are various treatment methods of traditional Chinese medicine. This article reviews a large number of clinical observations to clarify the effectiveness of traditional Chinese medicine in the treatment of post-stroke depression.

Traditional Chinese Patent Medicine in the Treatment of Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.

The objective of this study was to evaluate the efficacy and safety of Chinese patent medicine compared with western medicine in the treatment of Alzheimer's disease using the Network Meta-analysis. This study retrieved relevant studies from 7 databases, and the retrieval time was from the establishment of each database to June 2022. After the screening, data extraction, and quality assessment, 47 studies were finally analyzed, involving 11 Chinese patent medicines. The results demonstrated that Chinese patent medicine intervention was superior to oral western medicine treatment in improving the patient's condition as assessed by the Mini-mental State Examination (MMSE), Activities of Daily Living (ADL), effective rate, and Alzheimer's Disease Assessment Scale-Cognitive section (ADAS-Cog). Particularly, the effect of Chinese patent medicine combined with western medicine intervention was prominent. Meanwhile, Chinese patent medicine intervention in AD did not significantly increase the risk of adverse reactions. The results of the Network Meta-analysis demonstrated that Chinese patent medicine combined with western medicine had statistically significant differences in the MMSE score, ADL score, effective rate, and ADAS-Cog score, compared with both western medicine alone and Chinese patent medicine alone. In terms of adverse reactions, the difference between Chinese patent medicine intervention and simple oral western medicine was statistically significant. The results of further ranking probability analysis demonstrated that Chinese patent medicine combined with western medicine intervention ranked first in terms of MMSE, ADL, effective rate, and ADAS-Cog. Additionally, oral Chinese patent medicine intervention alone ranked first in reducing adverse reactions. In the funnel plots of the MMSE, ADL, and effective rate, most studies were symmetrically distributed on both sides of the midline, where small sample effects and publication bias might exist to some extent. However, this conclusion still needs to be combined with clinical syndrome differentiation and treatment, and more large-sample, multi-center, high-quality studies are needed for further verification.

Clinical Factors Affecting Platelet Growth in the Treatment of Aplastic Anemia by Tonifying Kidney and Generating Blood

Objective: To investigate the influence of kidney-tonifying and blood-generating method on platelet (PLT) growth in the treatment of aplastic anemia (AA) and analyze the characteristics of the clinical factors affecting PLT growth. We enrolled patients treated from September 2018 to March 2021 in the China Academy of Traditional Chinese Medicine (TCM) Xiyuan Hospital, China Academy of TCM hospital gate 19 sub-center. We enrolled 128 AA patients, for whom the inclusion criteria were: treatment is given priority to with kidney and heart’s-blood method, on the basis of western medicine treatment for kidney fill party avoid Fried instant particles, stay for 3 months for a period of treatment, taking two consecutive period of treatment, changes in the PLT were observed, and the clinical characteristics of AA patients, such as PLT growth and recovery from baseline value, were analyzed. Materials and Methods: A total of 128 AA patients from 19 branches of Xiyuan Hospital, China Academy of Chinese Medical Sciences and Guang’anmen Hospital, China Academy of Chinese Medical Sciences treated from September 2018 to March 2021 were enrolled. The treatment was based on the kidney-tonifying and blood-generating method and lasted for 3 months as a course of treatment. The changes in the number of PLT in patients were observed, and the clinical characteristics of AA affecting PLT growth and recovery from baseline value were analyzed. Results: After 6 months of treatment following the kidney-tonifying and blood-generating method, PLT increased from the baseline values in 75 cases, including 21 cases of AA with normal PLT recovery and 54 cases of AA without normal PLT recovery. There were 53 cases of AA in whom PLT did not increase from the baseline. Analysis of the general data showed that patients with lower Karnofsky Performance Status (KPS) score were more likely to experience PLT growth or even return to normal after therapy (P < 0.05). The results of routine blood analysis showed that when hemoglobin (HGB) was ≥60 g/L and the reticulocyte (RET) proportion was ≥0.3% before treatment, PLTs were more likely to increase, even returning to normal in some patients (P < 0.05). Analysis of bone puncture results before treatment showed that when the proliferation of nucleated cells was low or extremely low in bone puncture examination, with the proportion of granulocytes <40%, and the proportion of erythroid cells <20%, the treatment method was more effective at increasing PLT count (P < 0.05). Analysis of the chromosome karyotype results before treatment showed that when the chromosome karyotype was normal, PLTs were more likely to increase or even return to normal after treatment (P < 0.05). Analysis of T-lymphocyte subsets before treatment showed that when CD3+ human leukocyte antigen (HLA)-DR+ proportion was ≥30%, PLTs were more likely to increase or even return to normal (P < 0.05). Conclusions: AA patients with a low KPS score, higher HGB ≥60 g/L, RET proportion ≥0.3%, low or extremely low proliferation of nucleated cells, granulocytes proportion <40%, erythroid proportion <20%, normal chromosome karyotype, CD3+HLA-DR+ ≥30%, should be treated with a kidney-tonifying and blood-generating method. Such patients are more likely to show PLT growth and the values may even return to normal.

桡骨远端骨折的中西医治疗进展

桡骨远端骨折的中西医治疗进展

Meta-analysis and GRADE evaluation of Guanxinning Tablets in treatment of angina pectoris of coronary heart disease

This study aims to evaluate the efficacy and safety of Guanxinning Tablets+conventional western medicine in the treatment of angina pectoris of coronary heart disease, and provide evidence-based references for clinical medication. Retrieved from CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase, Cochrane Library, randomized controlled trial(RCT) about Guanxinning Tablets for the treatment of angina pectoris of coronary heart disease from the inception to April 2022 were collected. After literature screening and data extraction, the bias risk assessment tool recommended by the Cochrane evaluation manual handbook 5.1.0 was used to evaluate the quality of the included literature, and RevMan 5.3 and Stata 14.0 were used for Meta-analysis. Eighteen RCTs were finally included, involving 2 281 patients. Meta-analysis showed that, compared with conventional western medicine treatment alone, Guanxinning Tablets+conventional western medicine significantly improved angina pectoris efficacy(RR=1.33, 95%CI[1.13, 1.57], P=0.000 8), electrocardiogram efficacy(RR=1.32, 95%CI[1.02, 1.71], P=0.03), and exercise duration(MD=59.53, 95%CI[39.16, 79.90], P<0.000 01) and reduced the incidence of cardiovascular events(MACE)(RR=0.43, 95%CI[0.30, 0.61], P<0.000 01), high sensitivity C-reactive protein(hs-CRP)(MD=-2.75, 95%CI[-3.71,-1.79], P<0.000 01), and endothelin-1(ET-1) levels(MD=-9.34, 95%CI[-11.36,-7.32], P<0.000 01). There was no statistically significant difference in the incidence of adverse reactions between two groups(RR=0.91, 95%CI[0.68, 1.22], P=0.52). Subgroup analysis showed that Guanxinning Tablets may have better short-term efficacy(less than 6 months) in the treatment of heart-blood stasis syndrome. GRADE grading showed that angina pectoris efficacy, electrocardiogram efficacy, MACE, and ET-1 were in the medium grade, hs-CRP and adverse reactions were in the low grade, and exercise duration was in the extremely low grade. In conclusion, the efficacy of Guanxinning Tablets+conventional western medicine is better than conventional western medicine treatment alone, with good safety. Therefore, it is recommended for the short-term treatment of patients with heart-blood stasis syndrome. However, the evidence quality of some results is low, and more rigo-rous RCT is still needed to enhance the reliability of evidence.

The Antidepressant Mechanism of JiaWeiWenDan Decoction Regulating p38MAPK-ERK5 Signal Transduction Pathway

Objective: To investigate the anti-depression mechanism of JiaWeiWenDan Decoction in regulating p38MAPK-ERK5 signal transduction pathway. Methods: Depression model rats were randomly divided into Blank Control Group, Model Control Group, Chinese Medicine Treatment Group, and Western Medicine Treatment Group (hereinafter referred to as Blank Group, Model Group, Chinese Medicine Group, and Western Medicine Group), with 48 rats in each group. The mice were treated with p38MAPK-ERK5 on the 7th day, 14th day and 21st day, respectively, and the mice were treated for 28 days. The key targets and cytokines in p38MAPK-ERK5 signal transduction pathway were detected. Results: Compared with the Blank Group, the expression of p38MAPKmRNA in the hippocampus of the Model Group was increased. The Chinese Medicine Group and Western Medicine Group could reduce the expression of p38MAPK mRNA (P P P P < 0.05); There was no significant difference between the Chinese and Western Medicine Groups. Conclusion: The anti-inflammatory effect of JiaWeiWenDan Decoction may be related to the regulation of p38MAPK-ERK5 signaling pathway. With the advance of the treatment week, the best effect was obtained when the treatment was started on the 7th day of modeling.

Progress in Chinese and Western Medicine Treatment of Postoperative Lower Limb Lymphedema in Gynecologic Malignancies

Progress in Chinese and Western Medicine Treatment of Postoperative Lower Limb Lymphedema in Gynecologic Malignancies

Research Progress in Chinese and Western Medicine Treatment of Ulcerative Colitis with Anxiety and Depression

Research Progress in Chinese and Western Medicine Treatment of Ulcerative Colitis with Anxiety and Depression

Research Progress of Chinese and Western Medicine Treatment for Diarrheal Irritable Bowel Syndrome

Research Progress of Chinese and Western Medicine Treatment for Diarrheal Irritable Bowel Syndrome

Current research on Chinese and Western medicine treatment of prolonged menstruation due to uterine scar diverticulum

The clinical symptoms of CSD are prolonged menstrual periods, which often last more than 7 d or even half a month. This not only causes great psychological burden to patients, but also significantly reduces the quality of life. With the opening of China's three-child policy, the rate of cesarean section is increasing year by year, and the number of cases of prolonged menstruation due to CSD is increasing. In recent years, many scholars have done a lot of clinical research on the application of Chinese medicine for the treatment of prolonged menstruation due to CSD, and have achieved more satisfactory results.

건강보험심사평가원 환자표본 데이터 분석을 통한 한의 의료 이용 요추 수술 환자의 탐색적 성과 분석

Objectives This study aimed to analyze the medical utilization of low back pain (LBP) patients after back surgery and estimate the medical costs of Korean and Western medicine collaborative treatment, odds ratio, and hazard ratio between the two groups using the 2019 Health Insurance Review and Assessment Service-National Patient Sample (HIRA-NPS-2019). Methods Data management and descriptive analysis, logistic regression, and survival analysis were conducted for defining and estimating the LBP patients after back surgery in the NPS 2019 dataset. Results A total of 216,424 patients out of 991,189 were identified as having LBP. Among the patients with LBP, 1,734 were treated with surgery while 214,690 were not. Among those who had surgery, 937 were treated with conventional treatments only and 797 underwent Korean medicine treatments. The odds ratio of the logistic regression analysis was 0.7129, suggesting that Korean medical treatment experience group had a 28.7% lower risk of reoperation than the Western medical treatments only group. The hazard ratio of the survival analysis was 0.9145; thus, the risk probability of reoperation was estimated to be approximately 8.55% lower. The 50% risk of reoperation was 69 days (0.5044) for the conventional group, and 97 days (0.5008) for the Korean medical group in the survival analysis using the Kaplan-Meier graph. Conclusions These results could be utilized in future studies in conducting economic evaluation for estimating cost-effectiveness of Western medicine and Korean medicine treatment compared to Western medicine alone in LBP patients after back surgery in a South Korean perspective. mended and should be applied while taking the necessary precautions.