Western Medicine Treatment Research Articles

Antiviral and anti-inflammatory effects of medicated thread moxibustion combined with Shujin Jiannao granule in the treatment of HFMD

Objective To investigate antiviral and anti-inflammatory effects of medicated thread moxibustion combined with Shujin Jiannao granule in the treatment of HFMD. Methods A total of 124 children with HFMD were collected to divided into western medicine group (62 cases) and experimental group(62 cases) while 62 healthy children were enrolled to become normal control group. Western medicine group was treated according to conventional therapy while experimental group was treated with combined treatment of traditional Chinese medicine(TCM) and western medicine. To determine serum levels of S100B, NSE, CRP and WBC and observe the clinical effectiveness. Results In the western medicine group the total effectiveness rate is 88.7% while it is 96.8% in the experimental group（P<0.05）; the average disappearance time of symptoms are shorter in the experimental group than that in the western medicine group（P<0.05）. Compared with the control group，the serum levels of S100B, NSE, CRP and WBC all rise in HFMD children（P<0.05 or P<0.01）. After treatment , the serum levels of S100B, NSE, CRP and WBC reduce in both the experimental group and the western medicine group, when compared with that before treatment.The difference is statistically significant（P<0.05 or P<0.01）.

Comparative efficacy of Chinese herbal injections for treating chronic heart failure: a network meta-analysis

BackgroundOn account of deterioration of chronic heart failure (CHF) and extensive exploration of Chinese herbal injections (CHIs), we performed a network meta-analysis to investigate the efficacy of CHIs (Huangqi injection, Shenfu injection, Shengmai injection, Shenmai injection, Shenqi Fuzheng injection, Yiqifumai injection) on the basis of western medicine (WM) treatment in CHF.MethodsLiterature search was conducted in Embase, the Cochrane Library, Pubmed, Chinese Biological Medicine Database, China National Knowledge Infrastructure, Wanfang Database, Chinese Scientific Journal Database from inception to June 12nd 2017, and study selection was abided by a prior eligible criteria.ResultsUltimately, a total of 113 randomized controlled trials (RCTs) were enrolled. The clinical data of the effective clinical rate, left ventricular ejection fraction, cardiac output and others outcomes was estimated by Stata software and Winbugs software. Risk of bias was assessed by Cochrane Collaboration’s tools. Integrating the each outcome’s results, a combination of Shengmai injection/Shenmai injection and WM obtain a first rank in most outcomes, particularly primary outcomes.ConclusionsIn conclusion, on the basis of WM, Shengmai injection or Shenmai injection may be a perforable treatment in CHF. In terms of insufficient of this study, more high quality RCTs needed to implement to support our conclusions.

Meta-analysis on efficacy and safety of combination therapy of Aconitum and Western medicine in treatment of rheumatoid arthritis

To analyze the efficacy and safety of the combination therapy of Aconitum and Western medicine in the treatment of rheumatoid arthritis (RA) by Meta-analysis, and provide evidence for its clinic application for RA. The random clinical trials (RCTs) regarding the combination therapy for treating RA were retrieved in the database of China National Knowledge Infrastructure database, China Science and Technology Journal database, WanFang, Chinese Biomedical Medical Database, PubMed, and Cochrane Library up to July 2017. According to the given inclusion criteria, 8 RCTs involving 659 participants were included, and the included RCTs could be further divided into three subgroups according to the herb type, which were Aconiti Radix (Chuanwu) subgroup (6RCTs), Aconiti Kusnezoffii Radix (Caowu) subgroup (1RCT), and Chuanwu-Caowu subgroup (1RCT). The Meta-analysis results indicated that as compared with Western medicine, the combined use of Aconitum and Western medicine, no matter Chuanwu, Caowu or Chuanwu-Caowu subgroups, could improve the total effective rate of RA (6RCTs, RR=1.19, 95%CI [1.10, 1.28], P<0.000 01), (1 RCT, RR=1.43, 95%CI [1.18, 1.73], P=0.000 2), (1 RCT, RR=1.27, 95%CI [1.02, 1.58], P=0.03) respectively. The combined use of Aconitum and Western medicine was also effective on the number of joint swelling, duration of morning stiffness, patients' handgrip, and the erythrocyte sedimentation rate, C-reactive protein and rheumatoid factor. However, its action was not significant on joint tenderness. And also, in the included RCTs, there were 34 cases of adverse drug reactions/events (ADR/ADE) in the Chuanwu subgroup, while 86 cases in the Western medicine control group. The ADR/ADE incidence was even more lower in Chuanwu-Caowu subgroup, but no difference between Caowu subgroup and Western medicine group. Based on the included RCTs, the combined use of Aconitum and Western medicine could achieve more satisfying efficacy and lower ADRs incidence for RA as compared with Western medicine alone. However, due to the limitation in the not-high quality of included RCTs and the lack of large-scale multi-center research, the results still need to be further validated in the clinic application.

中西医治疗子宫内膜异位症研究进展

子宫内膜异位症是妇科疾病的常见病，其具体发病机制与病机并不十分清楚。子宫内膜异位症主要引起下腹盆腔疼痛、月经增多、痛经、性交不适以及月经异常等。关于子宫内膜异位症的治疗目前并未有明确的治疗方案，且难以治愈，西医治疗对与子宫内膜异位症的治疗药物剂量大、副作用多，而中医治疗则疗程长、起效慢，本文即将目前中西医对于子宫内膜异位症的治疗方案作一综合性叙述。 Endometriosis is a common disease of gynecological diseases; the pathogenesis and mechanism are not very clear. The main symptoms are pelvic pain, menorrhagia, dysmenorrhea, sexual discomfort and abnormal menstruation. It is intractable and no definite treatment for currently. Western medicine treatment exists large dosage of drugs with side effect; meanwhile Chinese medicine is long course of treatment and slow effect. This paper reviews the recent Western and Chinese medicine treatment for endometriosis comprehensively.

Ischemic Stroke Patients' Decision-Making Process in Their Use of Western Medicine and Alternative and Complementary Medicine.

Stroke is ranked third among the top 10 causes of death in Taiwan. Besides a high mortality rate, stroke survivors are often left with physical or functional sequela. This study aimed to explore ischemic stroke patients' decision-making process using Western medicine (WM) and complementary and alternative medicine (CAM). This study is a qualitative study based on grounded theory. A total of 12 participants were recruited. Findings revealed that the participants accepted WM and CAM treatments following the onset of ischemic stroke. Three categories and several subcategories emerged from stroke patients' decision-making process. These are "uncertainty of stroke," "delicate balance between WM and CAM," and "reestablishing confidence and faith." Eventually, they exhibited the core category of "breakthrough and the pursuit of a sense of rebirth." This study also found that the participants were unwilling to inform their health care professionals on their use of CAM. Therefore, health care professionals should empathize with the views and needs of their patients and respect their decision to combine WM with CAM. The views of other medical teams concerning CAM into their analysis of patients' decision-making process are recommended. Therefore, comprehensive insight into ischemic stroke patients' decision-making process for using CAM can be further explored.

浅析梦交致胎漏、胎动不安中医证治

自古以来关于梦交引起胎漏、胎动不安的病例并不少，而其相关医籍记载颇少，西医对于性梦及其所致自然流产治疗手段较少，收效欠佳，而中医对于该病的认识自两千多年前就已有所提及，至张仲景总结出用桂枝龙骨牡蛎汤论治心肾不交之梦交，及后世医家多方临证总结，对于梦交及其引起的胎漏、胎动不安辨证论治，综合治疗，疗效可靠，具有一定的优势与特色，故此浅析。 Since the ancient times, there are lots of cases about sexual dream leading to Fetal Bleeding or Fetal Irritability, but the related medical records are quite few, western medicine treatment means is less, poor results. However, Chinese medicine for the understanding of the disease would date from more than two thousand years ago, Zhangzhongjing summarized with Cinnamomi with Dragon's Bone and Oyster shell Decoction to treat heart-kidney imbalance of sexual dream, and later ages made the acknowledgement concluded in many ways, for the disease that treatment based on syndrome differentiation is comprehensive, the curative effect is reliable, Chinese medicine has certain advantages and characteristics. Therefore, here is a short analysis.

Efficacy and safety of Buyanghuanwu decoction combined with regular western medicine treatment for ischemic stroke convalescence: a systematic review and meta-analysis

Efficacy and safety of Buyanghuanwu decoction combined with regular western medicine treatment for ischemic stroke convalescence: a systematic review and meta-analysis

Effect and safety of press-needle on chronic heart failure

ObjectiveTo evaluate the effect and safety of the press-needle on chronic heart failure. MethodsAccording to the inclusion criteria and exclusion criteria, we screened 60 inpatients with chronic heart failure, from the Department of Cardiology in the Traditional Chinese Medicine Affiliated Hospital of Southwest Medical University, 60 cases were randomly divided into treatment group (n = 30) and control group (n = 30) in accordance with the random number table. The control group received standard Western Medicine treatment (according to the Chinese guidelines for the diagnosis and treatment of heart failure 2014 and patients' condition). The treatment group received the press-needle treatment on the basis of standard Western Medicine treatment, both treated for 3 months. Observing the 6 min walking distance (6 MWD), the score of Minnesota living with heart failure questionnaire (MLHFQ), N-terminal pro-brain natriuretic peptide (NT-proBNP), angiotensin II (Ang II), left ventricular ejection fraction (LVEF) before and after treatment. ResultsNo statistical differences were found between control group and treatment group at baseline. Through self-matching test before and after treatment, the observation indexes were improved (P < 0.05). When compared with control group, 6MWD increased, the MLHFQ, NT-proBNP, Ang II decreased in treatment group, and the difference was statistically significant (P < 0.05). There was no significant difference between the two groups regarding to LVEF (P > 0.05). ConclusionThe treatment of press-needle can significantly improve exercise tolerance and quality of life of patients with chronic heart failure, but the improvement of left ventricular ejection fraction was not significant.

Different Survival Benefits of Chinese Medicine for Pancreatic Cancer: How to Choose?

To assess the efficacy of Chinese medicine (CM) on patients with pancreatic cancer (PC) in a retrospective population-based study. Between January 1, 2013, and August 30, 2016, according to whether received Western medicine treatment, the patients were included into either integrative medicine (IM) group or CM group. All enrolled patients were orally administrated with Gexia Zhuyu Decoction () or Liujun Ermu Decoction () by syndrome differentiation, twice a day, last for at least 2 months. The primary end point was overall survival (OS). A total of 174 patients with PC were enrolled in this study. In stage I/II, the median OS was 20.5 months in the IM group [95% confidence interval (CI), 12.499 to 28.501] and 11.17 months in the CM group (95% CI, 5.160 to 17.180, P=0.015). The 1- and 2-year survival rates for the two groups were 47.0%, 40.0% and 21.0%, 21.0%, respectively. In stage III/IV, median OS was 13.53 months (95% CI, 8.665 to 18.395) in the IM group versus 6.4 months (95% CI, 0.00 to 15.682) in the CM group, respectively (P=0.32). The 1- and 2-year survival rate for the IM and CM groups were 27.0%, 7.0% and 20.0%, 2.0%, respectively. Intervention of CM contributes to the different survival benefits for PC in different stages. Multimodality treatment might be a promising strategy for PC patients in early stage. While, in advanced stage, CM might be an alternative candidate for PC patients.

Analysis of the effect of traditional Chinese medicine fumigation and washing for hemorrhoids

Objective To observe the application effect of traditional Chinese medicine fumigation in the treatment of hemorrhoids. Methods 80 patients with hemorrhoids were chosen as the research subjects, they were randomly divided into two groups.40 cases in the control group received conventional western medicine treatment, 40 cases in the observation group were treated by traditional Chinese medicine fumigation.The symptom scores before and after treatment, the symptoms disappear time and clinical effect were compared between the two groups. Results The total effective rate of the observation group was 90%, which was significantly higher than 75% of the control group (χ2=4.12, P<0.05). After treatment, the anal pain, anal edema, anal pruritus, bloody symptom scores of the two groups were lower than before treatment, the symptom scores after treatment between the two groups had statistically significant differences (t=12.11, 13.02, 14.19, 12.09, all P<0.05). The disappearance time of anal pain, anal edema, anal urticant, bloody of the observation group were (4.1±0.2)d, (3.4±0.1)d, (4.0±0.2)d, (5.0±1.1)d, respectively, which were shorter than those of the control group [(6.9±0.5)d, (6.0±1.1)d, (6.8±1.1)d, (8.0±0.2)d], the differences between the two groups were statistically significant(t=13.10, 13.09, 14.18, 11.29, all P<0.05). Conclusion Chinese medicine fumigation in the treatment of patients with hemorrhoids, anal pain, anal edema, can significantly improve the patients' symptoms such as anal urticant, bloody, the clinical effect is superior to conventional western medicine treatment. Key words: Administration, topical; Drugs, chinese herbal; Hemorrhoids

Curative effect of assisted reproduction technology by Traditional Chinese Medicine multi-channel interventional therapy on 95 cases of in vitro fertilization and embryo transfer failure

ObjectiveTo evaluate the curative effect of Traditional Chinese Medicine (TCM) multi-channel interventional therapy on women with Assisted Reproductive Technology (ART) failure, to compare the curative effect of the dual therapy and triple therapy on women with ART Failure, and to choose the best TCM interventional therapeutic plan. MethodsThe 95 cases with ART Failure from West China second University Hospital of Sichuan University meeting the inclusion criteria were randomly divided into three groups:dual therapy group (31 cases), triple therapy group (33 cases) and control group (31 cases). According to the intervene treatment of in vitro Fertilization and Embryo Transfer (IVF-ET) long cycle scheme, the control group wait naturally for 3 months before IVF-ET. The dual therapy group take TCM prescription E of cultivating emotion and assisting reproduction and auricular acupoint therapy for 3 months before IVF-ET, then Western Medicine treatment progestin supporting as well as auricular application and Antai Recipe after IVF-ET transplantation. The triple therapy group take TCM prescription E of cultivated emotion and assisted reproduction, auricular acupoint therapy and retention enema of TCM, and combination treatment the same as dual therapy group after transplantation. The natural pregnancy number, the period condition of secondary IVF-ET and the improvement of the kidney deficiency, liver depression and blood stasis syndrome among those three groups were compared. ResultsIt was showed from analysis in 95 cases with ART failure that the number of natural pregnancy was as followings: 3 patients from the dual therapy group, 10 patients from the triple therapy group, and no patient from the control group. The comparison among three groups have statistical significance (P < 0.05). The treatment group is superior to the control group, while the triple therapy is superior to the dual therapy. The comparison of the condition of the fertility rate, clinical pregnancy rate, biochemical pregnancy rate and early abortion rate during the period of secondary IVF-ET between pre-therapy and post-treatment of both the dual therapy group and the triple therapy group have statistical significance (P < 0.05). The comparison of the improvement of the kidney deficiency, liver depression and blood stasis syndrome between pre-therapy and post-treatment of both the dual therapy group and the triple therapy group have statistical significance (P < 0.05). The comparison between three groups after treatment have statistical significance (P < 0.05). ConclusionTCM multi-channel interventional therapy can increase the natural pregnancy rate of patients with ART Failure (the triple therapy is superior to the dual therapy); it can increase the fertility rate, clinical pregnancy rate, and decrease the early abortion rate during the period of secondary IVF-ET; it can improve syndromes of kidney deficiency, liver depression and blood stasis.

Comparative observation of the effect of electroacupuncture combined with heat-sensitive moxibustion and western medicine for premature ovarian failure

ObjectiveTo compare the clinical efficacy between electroacupuncture combined with heat-sensitive moxibustion and western medicine for treatment of premature ovarian failure. MethodsEighty patients were randomly divided into an electroacupuncture combined with heat-sensitive moxibustion group (group A, n=40) and a western medicine group (group B, n=40). Zîgōng (▪ EX-CA 1), Xuèhâi (▪ SP 10), Gānshū (▪ BL 18) and Shènshū (▪ BL 23) were selected in group A, and acupuncture combined with heat-sensitive moxibustion were carried out. Climen was taken orally in group B. The score changes of menstrual cycle, tidal fever and sweatiness, emotional excitement, soreness and weakness of waist and knees, dizziness and tinnitus, as well as the cured and markedly effective rate of the patients in the two groups before and after two courses of treatment were compared. ResultsThe cured and markedly effective rate of group A was 72.5% (29/40), which was superior to that of group B (37.5%, 15/40) (P<0.05). The symptom scores were improved significantly in the two groups after treatment (all P<0.05), and the improvement in group A was superior to that in group B (all P<0.05). ConclusionThe efficacy of electroacupuncture combined with heat-sensitive moxibustion is superior to that of conventional western medicine in treatment of premature ovarian failure.

Clinical observation of integrated traditional Chinese and western medicine in the treatment of intractable hiccup caused by cerebrovascular disease Medicine

Objective To explore the clinical effect of integrated traditional Chinese and western medicine in the treatment of intractable hiccup caused by cerebrovascular disease. Methods A total of 74 patients with intractable hiccup caused by cerebrovascular disease were selected.The patients were randomly divided into observation group and control group according to random number table method.28 patients in the control group were given simple western medicine treatment.46 patients in the observation group were treated with integrated traditional Chinese and western medicine.The total effective rate and symptom improvement were observed after treatment. Results The total effective rate of observation group was 94.48%, that was 78.57% in the control group, the difference was statistically significant (χ2=2.0, P<0.05). Conclusion Combined traditional Chinese and western medicine can significantly reduce intractable hiccup caused by cerebrovascular disease, improve total efficacy, improve the quality of life. Key words: Hiccup; Basal ganglia cerebrovascular disease

Morbidity pattern of traditional Chinese medicine primary care in the Hong Kong population

Primary care manages >90% of illnesses requiring medical services in Hong Kong, in which 9,513 registered Chinese medicine practitioners (CMPs) provide 8.2% of the consultations. This is the first study aimed to determine the morbidity pattern in different Traditional Chinese Medicine (TCM) primary care settings in Chinese population. 55,312 patients’ encounters were classified by the International Classification of Primary Care-2 (ICPC-2) from 260 of CMPs. Mean patient age was 50.5 years, with more females than males (67.0% vs 33.0%). Most patients consulted CMPs for chronic (64% vs 33.7%) rather than acute conditions. Among the 30% of patients, hypertension (49.5%) or diabetes (18.5%) were the most common co-morbidity. The most common problems presenting to CMP were respiratory (24.9%), musculoskeletal complaints (22.7%), cough (11.7%), and lower back pain (6.6%). To our knowledge, this was the first study permitting direct comparison with that presenting to Western medicine (WM) primary care by ICPC-2 systems. The results confirmed the role of CMP in primary care for musculoskeletal or chronic illnesses that they may have also received conventional WM treatment. We recommend greater effort and more resources should be invested to promote interdisciplinary communication to ensure safety and synergy of TCM and WM in primary care.

Efficacy and safety of rhubarb aconite decoction combined with acupoint application in the treatment of chronic renal failure (CRF)

Objective To study the efficacy and safety of rhubarb aconite decoction combined with acupoint application in the treatment of chronic renal failure (CRF). Methods 106 cases of CRF patients were randomly divided into two groups, the control group of 53 cases of conventional Western medicine treatment, the treatment group of 53 cases of rhubarb aconite combined with acupoint application, 2 groups were treated continuously for 20 d. (UA), blood urea nitrogen (BUN) and endogenous creatinine clearance (Ccr) were measured before and after treatment. The levels of serum creatinine (Cr), serum creatinine (UA), blood urea nitrogen (BUN) and endogenous creatinine clearance (Ccr) were measured and compared. Level, and observe the occurrence of adverse reactions during the two groups of treatment.

Efficacy of integrated traditional Chinese medicine with Western medicine in patients with diarrhea-predominant irritable bowel syndrome and its relation to serum inflammatory cytokines

Objective To investigate the efficacy of integrated traditional Chinese medicine (TCM) with Western medicine in treatment of diarrhea type irritable bowel syndrome (IBS-D) and its effect on serum inflammatory cytokine levels. Methods One hundred and sixty four IBS-D patients treated in Guangfu Hospital from July 2013 to August 2015 were randomly divided into study group and control group with 82 cases in each group. All patients received oral Saccharomyces boulardii 1.0 b. i.d, while patients in study group received additional Shuganjianpi decoction b. i.d for 4 weeks. The clinical efficacy was observed, serum IL-10, IFN-γ and TNF-α levels were measured in 2 groups. Results After treatment, the total score of clinical symptoms in study group was lower than that of control group [(5.71±1.41) vs. (11.70±2.88) points, t=16.707, P<0.01]. Serum levels of IFN-γ, TNF-α in study group decreased significantly after treatment [IFN-γ (2.88±1.38) ng/L vs. (1.00±0.44 ) ng/L, t=11.609, P<0.01; TNF-α (41.26±5.29) ng/L vs. (24.13±3.27) ng/L, t=24.636, P<0.01], IL-10 significantly increased [(142.23±21.58) ng/L vs.(170.23±33.45) ng/L, t=6.291, P<0.01]. The overall effective rate of study group was higher than that of control group, [87.50% (70/80) vs. 68.75% (55/80), χ2=8.228, P<0.01]. After treatment, the quality of life scores in both groups were improved; but the improvement of diet, spirit, mood and sleep scores in study group were better than those in control group [(240±69) vs. (193±60), t=4.579, (316±74) vs. (230 ± 69), t=7.603, (297±62) vs. (228±59), t=7.211; (284±62) vs. (230±54), t=5.874, all P<0.01]. Conclusion The efficacy of integrated traditional Chinese medicine with Western medicine in treatment of IBS-D is significantly better than that of Western medicine alone, which may be associated with its regulatory effect on the serum inflammatory cytokine levels. Key words: Integrated traditional Chinese medicine and western medicine; Irritable bowel syndrome; Cytokines

Observation of the clinical effects of strengthening spleen and tonifying lung Chinese medicine combined with western medicine treatment on 60 cases of acute stage of chronic obstructive pulmonary disease

Objective To study the curative effects of strengthening spleen and tonifying lung Chinese medicine combined with western medicine treatment on 60 cases of acute stage of chronic obstructive pulmonary disease (AECOPD). Methods 60 cases of AECOPD were randomly divided into the study group(30 cases) and the control group(30 cases) by the method of random number table.The study group received strengthening spleen and tonifying lung Chinese medicine combined with western medicine treatment, and the control group only received western medicine treatment.The therapeutic effect, pulmonary function, SGRQ scores, 6 MVD results and the clinical syndromes score were compared between the two groups. Results The cure relative indicators of the two groups showed no statistical difference before treatment (all P>0.05), and the effective rate in the study group (93.3%) was significantly higher than 63.3% in the control group (χ2=7.954, P=0.005). The results of 6 MVD of the two groups were significantly increased after treatment (all P<0.001), while the value of 6 MVD in the study group[(287±41)m]was significantly higher than (239±37)m in the control group after treatment (t=4.76, P<0.001). The SGRQ[(38.79±14.78) points]and the syndrome integral[(6.3±1.4) points]in the study group were lower than those in the control group (t=-2.439, -7.596, all P<0.05), while the syndrome integral of the two groups after treatment were significantly lower than before treatment (all P<0.001). The result of FVC of the two groups showed no statistical difference after treatment (t=1.169, P=0.247), while the levels of the FEV1(t=2.083, P=0.042) and FEV1 % (t=3.487, P=0.001) had statistically significant differences.Meanwhile, the FVC[(2.88±0.72)L]and FEV1[(1.91±0.5)L]in the study group were ascending after treatment (P<0.05), and the FEV1 % of the two groups were significantly increased after treatment (P<0.001). Conclusion Application of strengthening spleen and tonifying lung Chinese medicine combined with western medicine in the treatment of patients with AECOPD can significantly improve the lung function and reduce syndrome, which can improve the quality of life, with significant curative effects, so it is worthy of further clinical application and promotion. Key words: Pulmonary disease, chronic obstructive; Traditional chinese and western medicine treatment; Rengthening spleen and tonifying lung

Patients’ Perceptions of Korean Medicine Treatment for Osteoporosis in a Clinical Trial of an Osteoporosis Herbal Medicine Drug: a Qualitative Study

Objective This research aimed to understand patients’ perceptions of Korean medicine treatment for osteoporosis in a clinical trial setting. Methods Ten patients participating in a clinical trial of a herbal medicine drug for osteoporosis were invited to an interview. Data were collected by in-depth interviews and patient observations. This qualitative study adopted the case study research method, and within-case and cross-case analyses were conducted. Results A model of the patients’ osteoporosis management planning was derived from the study. The results showed that the patients’ perceptions of osteoporosis were derived from their knowledge and experience during diagnosis and treatment of the condition. Two groups of patients were recognized: those who overlooked the importance of osteoporosis and those who recognized the importance of osteoporosis. Before making treatment decisions about osteoporosis, the patients evaluated the treatment options and weighed the advantages and disadvantages of each option. When evaluating their treatment, the patients combined their knowledge and experience of Korean and western medicine treatments. Their experience of participating in the clinical trial influenced the management planning of osteoporosis. Two major reasons for low compliance with osteoporosis treatment were ignorance of the disease and insufficient information provided by doctors. Conclusion The results of this qualitative study pointed to four strategies that could be employed to improve accessibility to Korean medicine treatment for osteoporosis: the dissemination of comprehensive information on osteoporosis in the clinic and mass media, promotion of Korean medicine therapies for osteoporosis, management of clinical trial participants, and insurance coverage for Korean medicine. Keywords: osteoporosis, qualitative study, Korean medicine treatment, case study research, clinical trial, herbal medicine drug, perception

Clinical progress and problems of traditional Chinese and western medicine in children's adenoid hypertrophy

This paper reviewed the clinical research progress of the treatment of children's adenoid hypertrophy in recent years from the aspects of Chinese medicine treatment and combined traditional Chinese and western medicine treatment. It is believed thatTraditional Chinese medicine treatment for the children with adenoid hypertrophyhas showed better curative effect and less side effects, which can reduce the operation rates. It's easy for parents and children to accept and can be widely promoted in clinical. Key words: Adenoid hypertrophy; Traditional Chinese medicine; Clinical progress; Review

Clinical observation of yizhongshengxue capsule on the treatment of advanced gastric cancer-related anemia.

e21696 Background: Cancer-related anemia is an important factor that affects the clinical efficacy and quality of life for patients with advanced gastric cancer. This study is to observe the clinical efficacy of Yizhongshengxue Capsule, which is an herbal formula, on advanced gastric cancer-related anemia. Methods: A total of 96 eligible patients were randomized into three arms: 46 patients in the experimental arm, 26 patients in the positive control arm, and 24 patients in the negative control arm. All three arms received basic treatment of conventional medicine. Meanwhile, the experimental arm received Yizhongshengxue Capsule at the dosage of 3 capsules, 3 times daily. The positive control arm received Fufangejiao Syrup at the dosage of 20 ml, 3 times daily. The negative control arm received only basic treatment of western medicine. The course of treatment was 5 weeks. Results: After the 5-week-treatment, there was a statistically significant rise ( p&lt;0.05) of hemoglobin(HGB) in both experimental arm and positive control arm. The negative control arm had no statistically difference of HGB ( p&gt;0.05) before and after the treatment. Symptoms of dizziness, fatigue, loss of appetite, palpitation and insomnia in experimental arm were improved after the treatment ( p&lt;0.05). Symptoms of fatigue and loss of appetite in positive control arm were alleviated after the treatment ( p&lt;0.05). The negative control arm had no statistically difference in the above symptoms ( p&gt;0.05) before and after the treatment. Furthermore, there was a significant improvement of dizziness, loss of appetite, palpitation and insomnia in the experimental arm compared to the negative control arm ( p&lt;0.05). Finally, an improvement of the Karnofsky Performance Score(KPS) was seen only in the experimental arm after the treatment compared to that before the treatment ( p&lt;0.05). Conclusions: Our study shows that Yizhongshengxue Capsule can not only improve the clinical symptoms and quality of life in patients with advanced gastric cancer-related anemia, but also reduce or even reverse the trend of HGB decrease. Therefore, it is very promising in treating cancer-related anemia. Clinical trial information: ChiCTR-TRC-13003604.