The industrial sector’s water consumption is projected to increase by 400% by 2050, placing significant stress on freshwater reserves. To address this challenge, innovative solutions for water management are crucial. This paper proposes a comprehensive framework for Rainwater Harvesting (RWH) in industrial settings, offering a methodology to assess the potential for RWH implementation across EU industrial sites. The framework integrates internal and publicly available datasets, including EU climate change monthly average rainfall data from the Copernicus Climate Data Store, to create current and prospective scenarios for RWH. The methodology evaluates critical parameters co-created with industrial stakeholders, such as catchment area, water quality, and industrial water requirements. This approach allows for site-specific assessments, enabling industries to reduce freshwater consumption and support sustainability goals within the Horizon 2050 framework. Our findings indicate that implementing RWH systems can significantly contribute to a sustainable and circular economy by reducing annual freshwater consumption, promoting resource reuse, and lowering industrial water costs. This framework provides industries with a tool to assess RWH feasibility, supporting their efforts to prepare for increased water demands and contribute to environmental conservation.