Vomiting Research Articles

Introduction Given the worldwide prevalence of tooth wear and wear related to dental erosion a baseline understanding of the knowledge of populations related to erosive wear is required to maximize public health campaigns developed to address this condition. This research investigated the awareness of dental erosion, its causes, and protective factors among the general adult population of Trinidad and Tobago. Methods An anonymous de-novo questionnaire, developed using Google Forms and aligned with the CHERRIES framework for web-based surveys, was subjected to face validity to ensure the inclusion of content relevant to erosive tooth wear and clarity of items intended for a general population. The questionnaire was deployed on social media platforms (Facebook) and groups (WhatsApp Community Groups) specific to groups in Trinidad and Tobago for four months. Data was entered into SPSS (Version 29) and analyzed using cross-tabulations and Chi-squared tests. Results Of the 210 respondents, 39.2% had previously been diagnosed with tooth wear, 43.1 % believed they could identify erosive wear and 42.1% believed they could differentiate between predominantly erosive wear and dental caries. Sixty-two point nine percent of respondents identified sensitivity as a symptom of erosive tooth wear. Chi-squared tests on cross-tabulated data showed significant relationships between age and GERD causing erosive wear (p=0.03), heartburn causing erosive wear (p=0.049), eating disorders causing erosive wear (p=0.009), disorders with excessive vomiting causing erosive wear (p=0.005), excessive wine consumption (p=0.004). There were no significant statistical significances for cross-tabulated data on sex and the responses on causative factors. Conclusions Respondents were generally knowledgeable about the various types of foods, beverages, and medical conditions that may cause dental erosion but were unfamiliar with other factors that may influence erosion or protect against dental erosion.

Hyperemesis gravidarum is excessive nausea and vomiting in pregnant women to the point that it interferes with daily work because it generally becomes worse, due to dehydration. The aim of this study was to determine the relationship between nutritional status and hyperemesis gravidarum in pregnant women at the Langsa Lama Health Center, Langsa City in 2023. Case control research design, population of 68 pregnant women. The research results showed a relationship between nutritional status and the incidence of hyperemesis gravidarum in pregnant women at the Langsa Lama Health Center, Langsa City. Pregnant women with poor nutritional status will experience hyperemesis gravidarum 7.5 times compared to pregnant women with good nutritional status. It is recommended that health workers, especially those at Community Health Centers, always inform pregnant women about hyperemesis gravidarum and risk factors for hyperemesis gravidarum. Pregnant women are expected to always seek information about hyperemesis gravidarum and risk factors for hyperemesis gravidarum.

Introduction: Postpartum depression, a significant global concern yet a neglected domain that could have dire outcomes for both mother and children. This study aimed to find out the prevalence of postpartum depression among mothers in the Paropakar Maternity and Women's Hospital & explore the experiences of undergoing pregnancy and post-partum melancholy. Methods: A cross-sectional descriptive study with a mixed method approach and consecutive enumeration of sampling units were done among 271 participants at a maternity hospital, within the study period from July,2023 to Dec, 2023 after obtaining ethical approval (Reg no: 63/1992). Data collection was done through in-depth interviews for the qualitative part among the six respondents and self-administrative questionnaires were opted for the quantitative part among all the respondents. Results: Among the respondents, 203 (74.87%) fall within the 20-30 age range. Among them, 33 (12.24%) mothers experienced post-partum depression. Pregnancy and postpartum experiences were complex, with physical and mental challenges. Women often endured painful pregnancies, including excessive vomiting and pain. Mothers lacked support from family and spouses, impeding daily life and newborn care. Traditional superstitions often trumped medical advice, leading to confusion and risks. Despite challenges, some developed coping mechanisms, like self-counselling and community support.Conclusions: The study highlights the importance of pre-pregnancy assessment and depression screening for postpartum care. Social support is crucial, necessitating holistic support with education, mental health services, and destigmatization efforts for postpartum struggles.

Hyperemesis gravidarum is excessive nausea and vomiting in pregnant women that can interfere with maternal and fetal health. Ginger has long been used as a traditional medicine to treat nausea and vomiting. This study aims to determine the effect of giving ginger drink on reducing hyperemesis gravidarum in first trimester pregnant women.This research plan uses experimental method (pre-experiment), with one group pretest posttes design. The population in this study were 11 first trimester pregnant women who experienced hyperemesis gravidarum at the Keluarga Sehat Private Clinic. Data were collected using a questionnaire to measure the frequency of nausea and vomiting and observation to measure the severity of hyperemesis gravidarum. The results showed that from the data analysis using the t-test, it was found that t count t table, namely 4.183 2.228 and based on significance, it was found that the significance value was 0.05, namely 0.02, so ho was rejected and ha was accepted, meaning that there was an influence between the implementation of ginger drink in reducing hyperemesis gravidarum in 1st trimester pregnant women. There is a decrease in hyperemesis gravidaraum after being given ginger drinks, there is an effect of giving ginger drinks on reducing hyperemesis gravidarum in pregnant women in the first trimester at the Keluarga Sehat Private Clinic. (p value = 0.00).

Hyperemesis gravidarum is a condition of excessive nausea and vomiting in pregnant women that is worse than morning sickness, the cause is unknown. Psychological factors can worsen this condition, causing dehydration, weight loss, electrolyte imbalance, and complications such as liver damage and retinal hemorrhage due to increased blood pressure during vomiting. Treatment is done by administering fluids, glucose, electrolytes, and vitamins through an IV. This study aims to analyze the factors that influence the incidence of hyperemesis gravidarum at the Pagar Merbau Health Center, Deli Serdang, in 2023. This study uses a descriptive correlational method with a cross-sectional design to analyze the relationship between independent and dependent variables simultaneously. Data were collected retrospectively from 36 respondents using a purposive sampling technique. The research instruments were questionnaires and observation sheets, while data analysis was carried out using the chi-square statistical test which showed a p value = 0.021. There is a significant relationship between age, knowledge, parity, and multiple pregnancies with the incidence of hyperemesis gravidarum in pregnant women at the Pagar Merbau Health Center, Deli Serdang.

Latarbelakang: Prilaku kebiasan konsumsi makan yang kurang baik tidak dapat memenuhi kebutihan angka kecukupan gizi. Jumlah konsumsi makan dan jenis makan yang tidak sesuai gizi seimabng dapat berakibat gizi kurang, defesiensi zat besi dan kekurangan zat besi pada makanan. Mual muntah kehamilan memperburuk asupan nutrisi dan rawan beresiko terjadi anemia defesiensi zat besi. Tujuan penelitian untuk mengetahui factor prilaku konsumsi makan dan riwayat mual muntah dengan anemia kehamilan.Metode: Penelitian ini menggunakan desain Analitik Uji Lamda dengan rancangan cross sectional untuk mengetahui hubungan variable independen dengan dependen. Populasi berjumlah 40 orang. Teknik sampling: total sampling. Instrumen kuesioner data jumlah makan, data jenis makan dan riwayat mual muntah diperoleh dari wawancara. Data anemia diperoleh dari buku KIA hasil pemeriksaan hemoglobinHasil::Prilaku kebiasaan konsumsi jumlah makan ibu hamil ≤ 2kali sehari terdapat anemia sedang 6 orang (600%), dan anemia berat 2 orang (100%). Prilaku konsumsi gizi tidak seimbang mengalami anemia berat 2 orang (100%), anemia sedang 10 orang (100%), anemia ringan 6 orang (75%)Kesimpulan::tidak ada hubungan jumlah konsumsi makan dengan anemia, ada hubungan jenis konsumsi makan gizi seimabnag dengan anemia dan ada hubungan mual muntah dengan anemia pada kehamilan.Saran: Prilaku kebiasaan jumlah konsumsi makan yang cukup dan jenis makan gizi seimbang dapat mencegah terjadinya mual muntah berlebih dan anemia pada kehamilan. Kata Kunci: Jumlah Makan, Jenis Makan, Mual Muntah, Ibu Hamil ABSTRACT Introduction: Suboptimal dietary practices can lead to a failure in meeting the necessary nutritional demands. Insufficient food consumption and the intake of nutritionally imbalanced meals can culminate in malnutrition, iron deficiency, and a scarcity of iron in one’s diet. Pregnancy-induced nausea and vomiting can further deteriorate nutritional intake, thereby escalating the risk of iron deficiency anemia. The objective of this research is to discern the association between dietary behavior and a history of nausea and vomiting in relation to anemia during pregnancy.Methodology: This research employs an Analytical Lambda Test design with a cross-sectional framework to ascertain the relationship between independent and dependent variables. The study population comprises 40 individuals. A total sampling technique was utilized. Data pertaining to meal frequency, types of meals, and a history of nausea and vomiting were gathered through questionnaires. Anemia data were extracted from the KIA book’s hemoglobin examination results.Findings: Pregnant women who consume meals ≤ 2 times per day exhibit moderate anemia in 6 individuals (600%), and severe anemia in 2 individuals (100%). Those with unbalanced nutritional consumption experience severe anemia in 2 individuals (100%), moderate anemia in 10 individuals (100%), and mild anemia in 6 individuals (75%).Conclusion: There is no discernible correlation between meal frequency and anemia. However, a correlation does exist between the consumption of nutritionally balanced meals and anemia, as well as between nausea and vomiting and anemia during pregnancy.Recommendation: Sufficient meal frequency and the consumption of nutritionally balanced meals can mitigate excessive nausea and vomiting, and prevent anemia during pregnancy. Keywords: Meal Frequency, Type of Meal, Nausea and Vomiting, Pregnant Women

Abstract: Pregnancy is that wonderful period in a women’s life when she spends each and every day in pleasant anticipation, waiting to hold bundle of joy in her arms at the end of pregnancy. All women need health care and attention during pregnancy. When a woman becomes pregnant, she is very aware that a new life is growing with in her forth next nine months. Millions of women give birth to healthy babies every day. But on the other hand, there are women who have miscarriages, stillbirth or children with birth defects. This acts as a constant reminder of fragility and delicacy of the process from conception to child birth. It is along road with pitfalls at every turn. While most women negotiate the path to motherhood success fully, always at the back of their minds runs the thought that things can go wrong if they are not careful. This care helps pregnant women to be healthier and have fewer problems in birth Most women experience some type of morning sickness during pregnancy; however, some of them have extreme morning sickness called hyperemesis gravidarum, Hyperemesis Gravidarum is the strongest form of nausea and vomiting in pregnancy, defined as unrelenting nausea and excessive vomiting initiated before the 22nd week. The incidence of hospitalization for hyperemesis gravidarum is 0.3–3% of all pregnancies among all pregnancies and is the most common cause of hospital admission in the first trimester

Excessive nausea and vomiting result in a weak body, pale face and the frequency of urination decreases drastically so that body fluids are reduced, blood becomes thick (hemoconcentration) and can slow down blood circulation which means that oxygen consumption and tissue food are also reduced. The first trimester is the period when the fetus is in the early stages of the formation of body organs, if the mother suffers from excessive nausea and vomiting, it will result in the mother's nutrition not being met, this has a bad impact on the developing fetus, including causing slow fetal growth and BBLR. One of the non-pharmacological treatments to reduce nausea and vomiting is acupressure. Acupressure therapy to reduce nausea and vomiting is carried out by manually pressing on the pericardium 6 (PC 6) point in the wrist area. The purpose of this community service is to increase the knowledge of pregnant women in the first trimester about reducing nausea and vomiting with Pericardium 6 (Pc 6) acupressure. The activity method, carried out from February to August 2023 at PBM Yustati Ambarita, Jambi City, is a form of educational activity for pregnant women in the first trimester. After the education, a posttest was carried out using the same questionnaire with the pretest. The results of the education showed an increase in maternal knowledge after participating in the education. Before the education, 11 mothers had good knowledge and 19 mothers had poor knowledge. After education, all mothers have good knowledge about pericardium acupressure to overcome nausea and vomiting in pregnant women in the first trimester.

Pregnancy can cause changes such as an increase in hormones, one of which is nausea and vomiting. Hyperemesis Gravidarum is excessive nausea and vomiting in pregnant women which causes activities to be disrupted and the mother's condition worsens. The purpose of this study was to determine the description of the knowledge of pregnant women about hyperemesis gravidarum in the Batangtoru Community Health Center Work Area in 2024. This type of research is quantitative with descriptive method. The population in this study were first trimester pregnant women in the Batangtoru Community Health Center Work Area as many as 31 people December 2023 - February 2024, and the number of samples in this study were 31 people using the total sampling method. The analysis used was univariate. The results of the analysis showed that the knowledge of pregnant women about hyperemesis gravidarum in less knowledge as many as 12 people (38.7%). It is recommended for pregnant women to be more active in seeking information to health workers so that mothers get counselling about hyperemesis gravidarum and the dangers that can be caused to mothers and children so as to increase the knowledge of pregnant women about hyperemesis gravidarum.

Hyperemesis gravidarum is a condition of excessive nausea and vomiting during pregnancy. Thepurpose of this study is to knowsomefactor that associated with the incidence of Hyperemesis Gravidarum in first trimester pregnant women at Puskesmas Langkahan Kab. Aceh Utara , and in this study, three factors were taken,There are age, parity status, and employment. Themethod of this study uses a quantitative method with a cross sectional design. The sample of this study was amounted to 30 people using total sampling method. The Resultsof this study, using the chi-square test, obtained the value of Asymp. Sig on the age variable is 0.964; on the parity variable 0.092; and the employment variable is 0.374. These results indicate that this value is> 0.05, which means there is significant relationship between age, parity and employment with the incidence of hyperemesis gravidarum. Conclusion from the research conducted based on the relationship of factor related to the incidence of hyperemesis gravidarum,general,parity,and work there is a meaningful relationship.

Observational studies have previously reported an association between depression and certain female reproductive disorders. However, the causal relationships between depression and different types of female reproductive disorders remain unclear in terms of direction and magnitude. We conducted a comprehensive investigation using a two-sample bi-directional Mendelian randomization analysis, incorporating publicly available GWAS summary statistics. Our aim was to establish a causal relationship between genetically predicted depression and the risk of various female reproductive pathological conditions, such as ovarian dysfunction, polycystic ovary syndrome(PCOS), ovarian cysts, abnormal uterine and vaginal bleeding(AUB), endometriosis, leiomyoma of the uterus, female infertility, spontaneous abortion, eclampsia, pregnancy hypertension, gestational diabetes, excessive vomiting in pregnancy, cervical cancer, and uterine/endometrial cancer. We analyzed a substantial sample size, ranging from 111,831 to 210,870 individuals, and employed robust statistical methods, including inverse variance weighted, MR-Egger, weighted median, and MR-PRESSO, to estimate causal effects. Sensitivity analyses, such as Cochran's Q test, MR-Egger intercept test, MR-PRESSO, leave-one-out analysis, and funnel plots, were also conducted to ensure the validity of our results. Furthermore, risk factor analyses were performed to investigate potential mediators associated with these observed relationships. Our results demonstrated that genetic predisposition to depression or dysthymia was associated with an increased risk of developing PCOS (OR = 1.43, 95% CI 1.28–1.59; P = 6.66 × 10–11), ovarian cysts (OR = 1.36, 95% CI 1.20–1.55; P = 1.57 × 10–6), AUB (OR = 1.41, 95% CI 1.20–1.66; P = 3.01 × 10–5), and endometriosis (OR = 1.43, 95% CI 1.27–1.70; P = 2.21 × 10–7) after Bonferroni correction, but no evidence for reverse causality. Our study did not find any evidence supporting a causal or reverse causal relationship between depression/dysthymia and other types of female reproductive disorders. In summary, our study provides evidence for a causal relationship between genetically predicted depression and specific types of female reproductive disorders. Our findings emphasize the importance of depression management in the prevention and treatment of female reproductive disorders, notably including PCOS, ovarian cysts, AUB, and endometriosis.

Excessive nausea and vomiting is one of the complications of pregnancy that affects the health status of the mother and the growth and development of the fetus. If this nausea and vomiting occurs excessively, the nutritional intake of the fetus will be reduced which can cause impaired fetal growth. Based on a preliminary study at the Condong Health Center, there were 37 pregnant women who experienced nausea and vomiting, of whom 22 were unable to deal with nausea and vomiting properly. The purpose of this study was to provide education on how to deal with nausea and vomiting at the Condong Health Center in the hope that pregnant women can deal with nausea and vomiting in the right way. This study used the pre-experimental design method using the one group pretest and posttest design. Data collection was carried out by providing verbal education using leaflet media on how to deal with nausea and vomiting in pregnant women. Then the data was processed by a two-sample T-test using SPSS assistance. From the results of calculating the statistical test Paired Sample T-Test using SPSS showed a significant number between the pre- and post-test values with a significance value (2-tailed) p = 0.000, ≤ 0.05 where the alternative hypothesis (Ha) was accepted which means that there is an effect of providing education on attitudes of pregnant women about how to deal with nausea and vomiting in the first trimester at the Condong Health Center.

Introduction: Hyperemesis gravidarum (HG) is a pregnancy complication characterized by excessive nausea and vomiting. HG can cause dehydration, malnutrition, and other serious complications. In Indonesia, data regarding the experiences and coping strategies of pregnant women with HG is still limited.
 Methods: This research uses a qualitative design with a phenomenological approach. Data was collected through in-depth interviews with 10 pregnant women who experienced HG in Purwakarta Regency. Data were analyzed using qualitative data analysis methods.
 Results: The research results show that pregnant women with HG experience various kinds of physical and emotional symptoms. The most common physical symptoms are nausea, vomiting, fatigue, and dizziness. The most common emotional symptoms are anxiety, depression, and stress. Pregnant women use various coping strategies to deal with HG. The most common coping strategies are problem-focused coping strategies, such as seeking information about HG, consulting a doctor, and trying home remedies. Other coping strategies used are coping strategies that focus on emotions, such as seeking social support and relaxation.
 Conclusion: This research shows that pregnant women with HG experience a variety of physical and emotional symptoms. Effective coping strategies can help pregnant women to overcome HG and improve their quality of life.

Abstract Background Pediatric intestinal pseudo-obstruction (PIPO) is a rare, heterogeneous and severe gut motility disorder. It is associated with a high morbidity and mortality rate. The etiology of PIPO can be either primary (sporadic or familial), secondary or idiopathic. In primary forms, 50 to 75% of patients will present symptoms in the first month of life and 80% by the end of the first year of life. In 2014, Chetaille et al. described the CAID syndrome related to a recessive SGOL1 mutation as a new form of PIPO associated with cardiac dysrhythmia. Aims Our aim is to describe the clinical presentation and the specific digestive and nutritional features of pediatric patients with SGOL1 mutation. Methods Monocentric, retrospective and descriptive study. We enrolled children and adolescents aged less than 18 years. All data were collected from patients’ files. Results 8 patients were included (5 girls), two of them were first-degree related. They all had a typical clinical presentation of PIPO (excessive abdominal distension, abdominal pain and vomiting) but with a later onset than usually seen in primary PIPO (median (range) age: 6.3 years [2-15.6]). The median age (range) at diagnosis was 7.8 years [4-15.7]. In most patients contrast studies showed massively distended small bowel and colon. Antroduodenal manometry was performed in 6 patients and was abnormal with a neuropathic pattern. Others were diagnosed using the ESPGHAN criteria (2018 Jun;66(6):991-1019). All patients needed parenteral nutrition at a median (range) age of 11.8 years [6.5-15.9] due to failure to thrive, intestinal failure and electrolytic disorders. Seven patients needed an ileostomy. One out of 8 patients was off PN at 18 years. Three patients had sinus dysfunction: one at the time of PIPO diagnosis and two sometimes after. All of them required a pacemaker. One patient died in her twenties and it wasn’t related to PIPO or its possible complications. Conclusions Recessive SGOL1 mutation, a new cohesinopathy affecting the gut and heart rhythm, represents a late-onset but severe form of PIPO. It is usually associated with sinus dysfunction and cardiac dysrhythmia. However, digestive symptoms appear first. Long term outcome is still to describe. Funding Agencies None

Hyperemesis gravidarum (HG) is a pregnancy complication characterized by excessive nausea and vomiting, which can cause dehydration, electrolyte balance disorders and weight loss. The length of stay for HG patients in hospital can vary. This study aims to analyze the factors that contribute to the length of treatment for HG patients at Raja Ahmad Tabib General Hospital Tanjungpinang, Indonesia. This research was conducted with an analytical observational design with a retrospective approach. Data was collected from medical records of HG patients treated at Raja Ahmad Tabib General Hospital Tanjungpinang in the period January 2020 to December 2022. This was done using multiple linear regression. The dependent variable is length of treatment (days). The independent variables analyzed were maternal age, parity, severity of HG, nutritional status, and accompanying complications. A total of 100 HG patients were included in this study. The average length of treatment is 3.5 days. The results of the analysis showed that the factors that contributed to the length of treatment for HG patients were maternal age (p=0.02), parity (p=0.04), and severity of HG (p=0.001). Maternal age, parity, and severity of HG are factors that contribute to the length of treatment for HG patients at Raja Ahmad Tabib General Hospital Tanjungpinang.

Background: Hyperemesis Gravidarum is excessive nausea and vomiting during pregnancy. This nausea and vomiting can be dangerous for pregnant women because the intensity of the vomiting exceeds that of morning sickness (emesis gravidarum) which occurs early in pregnancy. Nausea and vomiting are physiological things that occur in early pregnancy, but nausea and vomiting that continues to get worse will cause hyperemesis gravidarum which can cause dehydration and acidoketosis. Ginger is a herbal plant that has long been known to prevent nausea and vomiting. Giving ginger candy is effective in reducing the frequency of nausea and vomiting in pregnant women in the first trimester. Objective: To identify the effectiveness of ginger candy against nausea and vomiting in pregnant women who experience hyperemesis gravidarum. Method: This study used the Quasy Experimental research method with a One Group Pretest Posttest design. The sample in this study was 30 pregnant women in the first trimester (0-12 weeks) who experienced nausea and vomiting. Results: The results of this study show that the average value before being given ginger candy was 15.50, while the average value after being given the treatment was 0.00. The results of giving ginger candy to pregnant women with hyperemesis gravidarum in the first trimester are quite effective.

ABSTRACT Chlorophyllum molybdites (Agaricaceae) is a toxic mushroom that occurs in Brazil, mostly in the southern region, where cases of poisoning due to accidental ingestion accumulate. In the Amazon region, the species is little known. Here we report the first confirmed occurrence record for the state of Pará. We expand the geographic distribution of C. molybdites and provide a morphological description of the specimens found, contributing to the knowledge of fungal diversity in the Brazilian Amazon region.

Background: Hyperemesis gravidarum is one of the problems encountered among pregnant women due to persistent and excessive vomiting starting before the end of the 22nd week of gestation. The current study aimed to assess the prevalence of hyperemesis gravidarum and associated factors among pregnant women at comprehensive specialized hospitals in northwest Ethiopia. Methods: A multi-facility-based cross-sectional study was conducted at comprehensive specialized hospitals from 1st June 2022 to 30th July 2022. The data were entered using EPI Data Version 4.6 statistical software and analyzed using SPSS Version 26. Descriptive statistics such as frequency, mean, and percentage were calculated. Univariable and multivariable binary logistic regression analyses were carried out to identify the associated factors of hyperemesis gravidarum. Results: In all, 404 study participants were enrolled. About 16.8% of pregnant women were found to have hyperemesis gravidarum. Age < 20 year (AOR = 3.170; 95% CI: 1.119, 8.980), study participants who cannot read and write (AOR = 5.662; 95% CI: 2.036, 15.7470), grade 1–8 (AOR = 4.679; 95% CI: 1.778, 12.316), and grade 9–10 (AOR = 8.594; 95% CI: 3.017, 24.481), being housewife (AOR = 6.275; 95% CI: 1.052, 37.442), living in urban area (AOR = 2.185; 95% CI: 1.035, 4.609), having previous hyperemesis gravidarum (AOR = 2.463; 95% CI: 1.210, 5.012), having family history of hyperemesis gravidarum (AOR = 2.014; 95% CI: 1.002, 4.047), unplanned pregnancy (AOR = 2.934; 95% CI: 1.030, 8.351), having recent abortion (AOR = 2.750; 95% CI: 1.010, 7.483), and gravidity (AOR = 1.956; 95%CI: 1.023, 3.737) were factors associated with hyperemesis gravidarum. Conclusion: The prevalence of hyperemesis gravidarum is higher. Low maternal age, lower educational level, being a housewife, being an urban resident, having previous hyperemesis gravidarum, having a family history, having an unplanned pregnancy, and having a recent abortion were significantly associated with hyperemesis gravidarum.

Chlorophyllum molybdites poisoning on Reunion Island

Hyperemesis gravidarum occurs more frequently in multiple pregnancies and hydatidiform moles than in pregnancies without other complications. Hyperemesis gravidarum is a symptom of excessive vomiting in pregnant women which causes weight loss (more than 5% of initial body weight), dehydration, ketosis, and abnormal electrolyte levels. This study aims to analyze the relationship between parity and nutritional status with the incidence of hyperemesis gravidarum at the Dendang Tirta Pratama Clinic, Stabat District, Langkat Regency in 2023. The type of research used in the research is a cross-sectional design. The research sample was 35 pregnant women at the Pratama Dendang Tirta Clinic, Stabat District, Langkat Regency using total sampling techniques. Data were analyzed by conducting a Chi-square analysis test. The results of the research were statistical tests using the Chi-Square test with the test results used being the Fisher Excat Test with a value of p = 0.012. Thus the p value < α 5%, 0.012 < 0.05. This researcher stated that there was a relationship between parity and nutritional status with the incidence of hyperemesis gravidarum. It is recommended that mothers always seek information about hyperemesis gravidarum and risk factors for hyperemesis gravidarum, so that during pregnancy mothers can consume nutritious food for the health of their fetus during pregnancy.