The study aimed to explore the key factors influencing the academic achievement of nursing students. Emphasizing the human capacity for self-directed learning and behavior, this research investigates the impacts of school values, teaching and learning, interest in courses, and learning engagement on students' academic achievement. The study aims to assess the current levels of these variables, design and implement Intervention Design Implementations (IDIs) to enhance them, and determine any changes in these variables before and after the implementation of IDIs. The research design was a sequential exploratory mixed-methods design, combining qualitative and quantitative methods to develop an instrument for data collection. With a sample size of 378, the target population was nursing students from higher vocational education in Shanghai, with a sample size of 378 students. Preliminary findings revealed that the school's values, teaching, and learning, interest in courses, and learning engagement were generally low. A multiple regression analysis showed that school value (p<0.05), teaching and learning (p<0.05), interest in a course (p<0.05), and learning engagement (p<0.05) significantly predicted academic achievement. Experts developed and validated a theoretical model based on the findings, laying the groundwork for future interventions aimed at enhancing nursing students' self-regulated learning capability. The study aimed to explore the key factors influencing nursing students' academic achievement in higher vocational education in Shanghai, China.
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