Molecular detection of Escherichia coli virulence factors in swine isolates: A systematic review and meta-analysis.

Unveiling the impact of atmospheric temperature on antifungal resistance and virulence factors in Candida spp. isolated from forest ecosystem.

Mobile genetic elements drive the assembly of high-risk resistance and virulence configurations at the riverine water-sediment interface.

Direct Evidence of Microplastic-Mediated Microbial Migration Across the River-Sea Transition via a Novel Field-Laboratory Coupled Approach.

Isolation, characterization and genomic analysis of three lytic bacteriophages (PBM) targeting Avian Pathogenic Escherichiacoli.

Global epidemiological trend of Klebsiella pneumoniae ST23: Emergence of KL57 lineage carrying dual carbapenemases.

Antimicrobial resistance and genomic characterization of Escherichia coli isolated from mink in northern China.

Isolation, characterization, and dairy application of a novel bacteriophage fBSPA4 against Salmonella enterica.

Diversity and potential environmental risks of DNA viruses on international ships' ballast water at Shanghai port, China.

Bioinformatic assessment of allergenicity, virulence, and secondary metabolites in Aspergillus species for industrial applications.

Adaptive responses of Porphyromonas gingivalis to hemin availability and temperature modulate the expression of its major virulence factors: a proteomic perspective.

New insights into host-dermatophyte interactions: pathogenesis, host defense mechanisms, and emerging clinical challenges.

Insights into antibiotic resistance gene dynamics during Tanfloc-induced flocculation-storage process for cyanobacteria removal in an algae-laden drinking water source.

Cyclic dipeptides inhibit Staphylococcus aureus biofilm formation and virulence via agr-quorum sensing, ica, and sarA pathways.

Pasteurella multocida toxin induces apoptosis of respiratory epithelial cells by activating the PERK-NF-κB-DR5 signaling axis.

Background and Aim: The present study aimed to investigate the pathogenic ability of Cronobacter sakazakii in neonatal mice through the evaluation of its effect on liver tissue and the associated histopathological changes . Methods: Isolates of C. sakazakii were obtained from the Microbiology and Molecular Laboratory, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, and were confirmed by 16S rRNA sequencing from samples of infant formula, spinal fluid, and blood. Forty-five neonatal mice aged between 10 and 16 days were obtained from the Iraqi Center for Cancer and Medical Genetics. The animals were divided into three experimental groups, the first group as a control and given only distilled water, the second and third group 10³ cells/ml , 10⁵ cells/ml administered of C. sakazakii (AIC) . Liver tissues were collected from the animals, processed for histopathological examination, sectioned, stained. Results: The results showed liver tissue was found represented by types of necrosis, including focal necrosis, hydropic and ballooning degeneration, swelling of liver cells vacuolated degeneration, congestion in blood vessels, extensive and diffuse hemorrhage , absent of normal structure of the liver cords, as well as The presence of many inflammatory cells in the liver is a sign of chronic inflammation . Conclusion: The study shows C. sakazakii causes severe liver damage in neonatal mice, linked to virulence factors OmpA and OmpX that aid adhesion and invasion. Though rare, infections are fatal in preterm infants. This model advances research on mechanisms, progression, and treatment.

Multi-targeted antimicrobial action of Juglone against Proteus mirabilis biofilm and virulence.

A Fusarium pseudograminearum secreted protein, Fp00392, is a major virulence factor during infection and identified as a PAMP

Mycoplasma bovis isolates from Chinese dairy farms: Analysis of genomic features, antimicrobial resistance, and virulence-associated structural differences.

Inhibition of the α7 nicotinic acetylcholine receptor alleviates pyroptosis in blood-brain barrier induced by Cryptococcusneoformans.