Valutazione Del Research Articles

Evaluation of a Motion-Based Platform for Practicing Phonological Awareness of Preschool Children

The aim of this study is to introduce a new platform, called En Plein, for the kinesthetic practice of phonological skills by preschool children and to examine its feasibility in combination with more traditional teaching methods. The rationale is that the manipulation of structural phonological units is important to train the necessary prerequisites for writing and reading and to help the identification of early learning disability precursors. The system includes a large number of phonological activities for children and allows interaction with a playful virtual environment via a cartoon-avatar controlled by a gesture-based natural user interface. En Plein relies on the Microsoft Kinect™ motion sensor. In the pilot study, the system has been placed in a classroom of an Italian kindergarten for 5 weeks of training. A test for assessing the phonological skills in Italian language for kindergarten (Valutazione delle Competenze Metafonologiche [CMF]) has been administered before and after training. Children who worked with the platform showed improvements in their phonological awareness (mean increase of CMF scores of 9%), while their peers who received only the traditional education had a mean increase of CMF scores of 1%. Results from this preliminary study show that children who used the system were more confident in manipulating structural phonological units, increased their awareness of words sound structures and generalized these skills by applying them to different tasks. The performance of En Plein is particularly encouraging for future large-scale applications in kindergartens and possible tests with children at risk of developing specific learning disabilities.

Early maternal relational traumatic experiences and psychopathological symptoms: a longitudinal study on mother-infant and father-infant interactions.

Early maternal relational traumas and psychopathological risk can have an impact on mother-infant interactions. Research has suggested the study of fathers and of their psychological profiles as protection or risk factors. The aim of the paper is to assess the quality of parental interactions during feeding in families with mothers with early traumatic experiences. One hundred thirty-six (N = 136) families were recruited in gynecological clinics: Group A included families with mothers who experienced early sexual/physical abuse; Group B was composed of families with mothers who experienced early emotional abuse or neglect; and Group C comprised healthy controls. The subjects participated in a 10-month longitudinal protocol [at the fourth month of pregnancy (T0), 3 months after child birth (T1), and 6 months after child birth (T2)] that included an observation of mother-infant and father-infant interactions during feeding (Scala di Valutazione dell’Interazione Alimentare [SVIA]) and a self-reporting 90-item Symptom Checklist-Revised (SCL-90-R). Maternal higher rates of depression and early traumatic experiences of neglect and emotional abuse predicted more maladaptive scores on the affective state of the dyad SVIA subscale. Paternal anxiety predicted more severe levels of food refusal in the child during feeding.

Mother-child and father-child interaction with their 24-month-old children during feeding, considering paternal involvement and the child's temperament in a community sample.

The article aims to study mother-child and father-child interactions with 24-month-old children during feeding, considering the possible influence of time spent by the parent with the child, the infantile temperament, and the parental psychological profile. The families were recruited from 12 preschools in Italy (N = 77 families). Through an observation of the feeding [Scala di Valutazione dell'Interazione Alimentare (SVIA - Feeding Scale; I. Chatoor et al., ; L. Lucarelli et al., )], self-reporting [Symptom Checklist-90-Revised (SCL-90-R; L.R. Derogatis, ), and report-form questionnaires [Italian Questionnaires on Temperament (QUIT; G. Axia, )], and information provided by the parents about the amount of time spent with their children, results showed that the overall quality of father-child interactions during feeding is lower than that of mother-child interactions. Fathers showed higher psychological symptoms than did mothers. No associations were found between the fathers' psychopathological risk and the quality of interactions with their children during feeding. Mothers' psychopathological risks predicted less contingent exchanges interactions with their children during feeding. Children's temperaments significantly influence mother-child interactions, but no association exists between maternal involvement and the quality of interactions with their children. Paternal involvement predicts a better quality of father-infant interactions when associated with a child's higher scores on Social Orientation. The quality of parents' interactions with their children during feeding are impacted by different issues originating from the parent's psychological profile, the degree of involvement, and from the child's temperament.

Trying to Raise (Low) Math Achievement and to Promote (Rigorous) Policy Evaluation in Italy

Italy is a country showing low math achievement, especially in the Southern regions. Moreover, national student assessments are recent and rigorous policy evaluation is lacking. This study presents the results of one of the first randomized controlled trials implemented in Italian schools in order to measure the effects of a professional development (PD) program for teachers on student math achievement. The program was already at scale when it was being evaluated. Assessing the effects of a PD program for math teachers on their students' achievement and making suggestions for future policy evaluations. A large-scale clustered randomized control trial has been conducted. It involves 175 lower secondary schools (sixth - eighth grade) in four among the Italian lowest performing regions. Alongside national standard math assessments, the project collected a wide amount of information. Math in lower secondary schools. Math achievement as measured by standardized tests provided by the National Education Assessment Institute (Istituto Nazionale per la Valutazione del Sistema di Istruzione e Formazione); teacher and student practices and attitudes collected through questionnaires. Findings suggest that the program had no significant impact on math scores during the first year (when the program was held). Nonetheless some heterogeneity was detected, as the treatment does seem "to work" with middle-aged teachers. Moreover, effects on teaching practice and student attitudes appear. Some effects attributable to the intervention have been detected. Moreover, this project shows that a rigorous approach to evaluation is feasible also in a context lacking attention towards evidence-based policies, such the Italian school system.

The National Evaluation System in Italy

The construction of a national service for the evaluation of the school system had a long and difficult birth in Italy, and lagging behind the international panorama. The first signals that show attention to this problem date back to 1990, at the National School Conference, where for the first time, a hypothesis about this was formulated. However, the times were not yet ripe for an institution of this kind: in fact, at that time there was lacking a centralized computer system capable of recording the data of the Italian school system. In 1997 the Minister of Education Giovanni Berlinguer, by a directive, instituted the National Service for the Quality of Education, with the task of "assessing the situation and the effectiveness of the country's training system, its different articulations to at all levels, in order to suggest the necessary improvements and to be able to compare our situation with comparable situations in other countries ”. This service is established at the European Center for Education (CEDE), an institution which belongs to the Ministry of Education and which also has the institutional tasks of learning problems and their evaluation. By legislative decree N ° 258 of 1999, the CEDE was transformed into a National Institute for the Evaluation of the Education System (INValSI) with a substantial extension of its tasks and purposes in the evaluation sector. The realization of this National Evaluation Service (SNE) was accelerated by the establishment, on the part of the Ministry of Education in July 2001, of a Working Group whose objective is to develop a service which provide, at different levels of decision and intervention (Ministry of Education, local authorities, schools) useful information for understanding the phenomenon of "school" and its behavior over the years; this information is essential so that each subject, at their level, can make an informed decision on the policies and objectives to be set, verify their activation and progress, allocate resources correctly, with a view to continuous improvement. The working group projected the SNE model and tested it in the field for three years, through three Pilot Projects (PP): PP1 (school year 2001-2002), PP2 (school year 2002-2003) and PP3 (school year 2003-2004), which are described in broad outline below. The objective of these Pilot Projects was to verify the technical and economic applicability of the initiative by making, if necessary, the adjustments suggested by experience. It is on the basis of this experience that the legislative decree (No. 286, November 2004) on the “Institution of the National Service for the Evaluation of the Education and Training System” was promulgated, which emphasizes the purpose of this service: assess the efficiency and effectiveness of the system "by framing the assessment in an international context" (art.1); the seat is redesigned and becomes, to face its new role, the INVALSI (Istituto Nazionale per la Valutazione del Sistema dell'Istruzione e della Formazione). Schools and training establishments, Regions, Provinces and Municipalities are also involved, each according to their skills, to achieve this objective.

Valutazione del potenziale rigenerativo di tipologie distinte di spazi verdi urbani e periurbani

Urban and periurban green spaces play an important role in preserving environmental resources and naturalness, with positive effects on people’s health and well-being. In this context, the study aims to model the relationship between the main ecological and psychological factors (e.g., biodiversity, perceptions, attitudes, evaluations, behaviors, etc.) that are related to urban and periurban green spaces. We focused on the psychological benefits and the general well-being associated with the use of green spaces. We selected five typologies of green spaces in the city of Bari (southern Italy), characterized by different physical features (e.g., presence of natural and built up elements, total extent of the area, distance from urban centre, etc.). A questionnaire focusing on people’s experience in the environment (length and frequency of visits, activities performed, perceived restorativeness, affective qualities of the place, perceived well being during and after the visits) was administered to users of five green space typologies. Results show that the perceived restorative properties are associated to typological characteristics of urban green spaces. Results suggest a mediating role of perceived restorativeness and length of the visits on the perceived well-being. We conclude by discussing the implications of the study on urban policies in the context of sustainability.

Nuovi mercati della valutazione: misurare l'impatto di uno sforzo addizionale territoriale in ricerca e innovazione

- Research and innovation policies have been increasingly ascribed to regions as a consequence of devolving power and resources from the national level to the local level. Local administrators have been empowered with new and challenging responsibilities but often lack the necessary instruments and knowledge to adequately evaluate the undertaken initiatives and to operate consistently with the European and national dimensions. In this respect impact assessment brings in a new metrics that is neither exclusively related to the scientific and/or economic value of the innovation results nor to a support function to other policies. Experts and/or ad hoc organisations are often appointed by local administrations with the task of describing the dimensions of such impact - qualifying (and quantifying) its descriptive parameters and identifying interested parties. So far this approach has not produced robust results as for the causality links generated, the additionality issue and the role of the local dimension, while the available tool-box is quite poor. This paper is intended to illustrate the results of a pilot experience carried out in the last few years in Trentino. The analysis takes into account the relations among policy makers, available tools, resources, and the role of the public administration and of professional evaluators. Conceptual and interpretative approaches and tools need further development, but the mayor weakness seems to come from the relationship between customer and evaluators. A new market based on new rules, professional roles and shared behaviours is needed in order to address a correct evaluation pathway and to analyse policies and activities within a common frame.Key words: impact analysis, regional development, research and innovation policy, policy EvaluationParole chiave: analisi d'impatto, sviluppo regionale, politica della ricerca e dell'innovazione, valutazione delle politiche

In and Out of the Capitalia Sample: Evaluating Attrition Bias

The Capitalia sample survey of manufacturing firms in Italy represents a potentially important source of panel data on Italian firms. To date 8 waves have been released the most recent of which takes the survey upto the year 2000. In each wave, data is collected for a three year period and resampling of the same firms allows the construction of a firm panel over a much longer period. The composition of such a panel for the 5th, 6th 7th and 8th waves covering the period 1989-2000 inclusive was undertaken as part of the PRIN 2003 research project Metodi e applicazioni per la valutazione delle politiche del lavoro e di aiuto alle imprese. In this paper, the characteristics of the sample are considered. In particular, sample entry and exit behaviour are studied in order to gain some understanding of the potential for using the database constructed at the University of Salerno for undertaking panel studies of firms over 2 or more waves of the survey. Such panels would be useful in many contexts, for example, in gaining a better understanding of the impact of industrial policies on indicators of firm success than has thusfar been possible with the analysis of single waves of the sample. Given the unique richness of the database in terms of the range of qualitative as well as quantitative information on Italian firms which it contains, the potential uses and usefulness of a panel dataset constricted from the Capitalia sample are extensive.

Behavioral and psychological symptoms of dementia (BPSD) in elderly demented subjects: Is the long lasting use of atypical antipsychotic drugs useful and safe?

The use of atypical antipsychotics (AA) is suggested in the treatment of BPSD, although controversial data are available on their safety and efficacy. The aim of this study was to assess the efficacy and safety of AA and whether this therapy could modify cognitive and functional domains in parallel with BPSD modifications. Out of 1,100 patients followed by the psychogeriatric ambulatory of our hospital, 69 patients (6.2%) were in therapy with AA and only 32 of them fulfilled the inclusion criteria of this study. Namely, the availability was required of a complete geriatric assessment, including the evaluation of cognitive (mini mental state examination = MMSE), emotional (the Italian “scala di valutazione del benessere emotivo nell’anziano” = SVEBA), functional (basic and instrumental activities of daily living = ADL and IADL), as well as behavioral (neuropsychological inventory = NPI) status, at the beginning (T 0) and after a 6 month therapy (T 1). The AA prescribed were risperidone (42.8%), olanzapine (31.3%), quetiapine (25.9%). The mean age was 80.1 years; 34.4% male; 65.6% female. Educational level was elementary in 90.6% of cases. Only 21.9% were institutionalized. 15.6% had 1 cardiovascular risk factor (CVRF), 50% more than 1, and the remaining with no CVRF. More than the half of them were diagnosed with degenerative dementia (D) (40.6% Alzheimer D = AD; 15.6% fronto-temporal dementia (FTD); 34.4% with vascular dementia (VD) (9.4%) or combined D (25%); 3,1 % with mild cognitive impairment (MCI), classified as F06.7 by the ICD-10 (International Classification of Diseases) and 6.2% with psychiatric disturbances. The most common BPSD were hallucinations, delusions, agitation, verbal and physical aggression. A paired t-test was applied to analyze data. There was a significant improvement with all 3 AA on NPI (mean NPI T 0 = 27.50 vs. T 1 = 12.13; t = 7.49). An improvement was also observed on SVEBA ( t = 1.97), close to significance. Most people did not have any adverse effects; 5 patients (15.6%) had extrapyramidal symptoms and 1 (3.1%) showed ginecomasty, clinically so relevant to cause the interruption of the treatment. The profile of safety and efficacy described on the whole sample was confirmed when it was subdivided according to kind of drug, illness severity and presence/absence of CVRF. In a large sample of the “real” subjects attending a geriatric service for dementia, the accurate selection of patients treatable with AA leads to identification of a population with a negligible rate of adverse effects in presence of a high rate of efficacy with respect not only to BPSD but also to cognitive and functional domains.

Relation of neurocardiovascular instability to cognitive, emotional and functional domains

There is bulk of evidence suggesting that blood pressure dysregulation, as low blood pressure (LBP) or hypotension, orthostatic hypotension (OH) and high blood pressure (HPB) or hypertension are associated with alterations in cognitive and emotional domains. Some studies suggest that LBP, neurocardiovascular instability, like the OH, and atherosclerosis resulting from long standing HBP, reduces cerebral blood flow, increasing the risk of cognitive impairment, morbidity and mortality. This study aims to evaluate whether patients with cognitive impairment and cardiovascular disease would show any differences in some anamnestic indicators and/or psychometric measures of cognitive performance and affective symptoms. We recruited 36 patients over 65 years of age admitted to both psycho- and cardio-geriatric ambulatories of our hospital during the last year. The population (mean age of 80.5 years, 72.2% females, 27.8% males) was divided in 2 groups, with OH (25%), and without OH (75%). The first group was subdivided in subgroups: patients with HBP, normal BP and LBP, respectively. Cognitive and depressive domains were assessed with the mini mental state examination (MMSE) and the Italian “scala di valutazione del benessere emotivo nell’ anziano” (SVEBA). Information about the present status, comorbidities (cumulative illness rating scale = CIRS), functional ability (activities of daily living = ADL, instrumental ADL = IADL) and drugs were collected during clinical examination. BP was measured 4 times, at the beginning of examination, then with the patient in clinostatic and orthostatic position (1st and 3rd minute). Data were analyzed by MANCOVA, considering age and gender as covariates, MMSE, SVEBA, CIRS, ADL, IADL and drugs as dependent variables, and presence/absence of OH as factor. Covariates were not significant sources of variance, as well as overall factor. Due to the heuristic aim of the study, we considered of interest the results of subsequent ANOVAs showing significant differences in SVEBA and ADL with respect to the factor. These data give us the basis to develop a longitudinal study to confirm the detrimental effect of OH on a wide range of health domains.

Outcome assessment of the VADO approach in psychiatric rehabilitation: a partially randomised multicentric trial

BackgroundRecent studies on representative samples of psychiatric services have shown that low proportions of cases received effective rehabilitation interventions. The following are likely to be the most important causes: the scarcity of mental health workers trained in social and work skills strategies and the absence of a structured framework to formulate rehabilitation practices.The aim of this study was to assess if a specific structured planning and evaluation manual, called VADO (Valutazione delle Abilità e Definizione degli Obiettivi – in english: Skills Assessment and Definition of Goals), is more effective than routine interventions in reducing disability in patients with schizophrenia.MethodEach of 10 mental health services were invited to recruit 10 patients with a schizophrenic disorder. Altogether 98 patients were recruited. Of these, 62 patients were randomly allocated to the intervention/experimental or a control group. The remaining group of 36 patients was not randomised and it was considered as a parallel effectiveness study. Assessment measures at the beginning of the study and at the one-year follow-up included the FPS scale of social functioning and the BPRS 4.0. Between group (VADO vs. Routine) and time effects were examined with ANOVA, Chi-square or Fisher exact. Clinical "improvement" was defined as an increase of at least ten points on the FPS or a decrease of at least 20% on BPRS scores.Results31 of the 62 randomized patients received the experimental interventions, while 31 followed the routine ones. At follow-up, the experimental group showed statistically and clinically greater improvements in psychopathology and social functioning.Better outcomes of both social functioning and symptom severity were observed in non randomised patients (parallel effectiveness study).ConclusionThe results suggest that setting personalised and measurable objectives, as recommended by the manual, can improve the outcome of rehabilitation of severe mental disorders. Better outcomes in the parallel effectiveness study could be attributed to the greater confidence and enthusiasm of staff in centres where the VADO approach originated.

Children with low motor ability have lower visual-motor integration ability but unaffected perceptual skills

The purpose of this study was to examine perceptual, visual-motor abilities and intellectual skills in children with low, average and above average motor abilities. The participants were 144 children (aged 6–10 years) attending elementary school. Three groups of children were identified on the basis of their performance at the TGMD (Test of Gross Motor Development; [Ulrich, D.A. (1985). TGMD, Test of Gross Motor Development. Austin, Texas: PRO-ED. Edizione Italiana a cura di D. Ianes, TEST TGM. Test di valutazione delle abilità grosso-motorie. 1994, Trento: Edizioni Centro Studi Erickson]). Each child received an intelligence test (K-BIT; [Kaufman, A.S., & Kaufman, N.L. (1990). K-BIT. Kaufman Brief Intelligence Test. Circle Pines, MN: American Guidance Service]) and was evaluated for perceptual and visual-motor integration abilities (DTVP; [Hammill, D.D., Pearson, N.A., & Voress, J.K. (1993). Developmental Test of Visual Perception (2nd ed.). Austin, Texas: PRO-ED. Edizione Italiana a cura di D. Ianes, TEST TPV. Test di percezione visiva e integrazione visuo-motoria. Trento: Edizioni Centro Studi Erickson]). Results highlight a significant difference in visual-motor integration between children with high and low gross-motor abilities, in the absence of significant differences in perceptual skills or intellectual ability. The findings are discussed with reference to the concept of atypical brain development [Gilger, J.W., & Kaplan, B.J. (2001). Atypical brain development: A conceptual framework for understanding developmental learning disabilities. Developmental Neuropsychology, 20, 465].

Anatomia TC ed RM della regione orbitaria

Pur non sottovalutando il ruolo degli US, la TC e la RM mostrano un ruolo di primo piano nella valutazione delle strutture ossee e del contenuto orbitario. Although ophthalmoscopy, fluoro-angiography and ultrasound can usually identify most bulbar lesions, CT and MR play a major role in assessing the bony orbital structures and the post-bulbar soft tissues. These imaging techniques are especially important in investigating the eyeball under conditions “blind” to ultrasound not transparent to dioptric instruments (blood in the vitreous body, cataract, corneal opacity) or to define the site and extension and sometimes the nature (melanoma) of tumours. Whereas both CT and MR are completely reliable techniques in the study of the orbit, overall CT is decidedly superior to MR in the study of bony structures and MR is the method of choice in assessing the endo-orbital contents. This is because MR offers better spatial resolution and contrast with multiplanar views (allowing study on three planes without requiring the patient to assume uncomfortable positions for coronal CT scanning), greater sensitivity to tissue changes and hence diseases, the lack of signal from bony tissue (displaying the content of small structures like the orbital apex, nasolacrimal fossa and optic canal which are difficult to assess by CT due to artefacts) and lastly, the absence of ionizing radiation in examining children. These advantages are flanked by the use of the fast-imaging technique and surface coils (phased-array) which have overcome the limitations originally linked with MR due to the prolonged examination times and images degraded by artefacts. Nowadays, the only obstacle to routine use of MR is the shortage of MR systems in Italy. For both MR and CT scanning, technological developments have led to significant advances with the advent of the spiral technique which reduces the artefacts of eyeball movements because anatomical volumes can be investigated rapidly, improving patient compliance (in acquiring coronal scans) and enhancing the quality of two and three-dimensional reconstructions and allowing optimum use of contrast medium as the structure can be scanned during the maximum increase phase with a reduction in the total amount of contrast administered. Although the spiral technique is seldom used to examine the orbit in adults given the small volume to investigate, it is particular indicated in uncooperative patients (children or trauma patients).

Traumatic grief as a risk factor for mental and physical morbidity.

The aim of this study was to confirm and extend the authors' previous work indicating that symptoms of traumatic grief are predictors of future physical and mental health outcomes. The study group consisted of 150 future widows and widowers interviewed at the time of their spouse's hospital admission and at 6-week and 6-, 13-, and 25- month follow-ups. Traumatic grief was measured with a modified version of the Grief Measurement Scale. Mental and physical health outcomes were assessed by self-report and interviewer evaluation. Survival analysis and linear and logistic regressions were used to determine the risk for adverse mental and physical health outcomes posed by traumatic grief. Survival and regression analyses indicated that the presence of traumatic grief symptoms approximately 6 months after the death of the spouse predicted such negative health outcomes as cancer, heart trouble, high blood pressure, suicidal ideation, and changes in eating habits at 13- or 25-month follow-up. The results suggest that it may not be the stress of bereavement, per se, that puts individuals at risk for long-term mental and physical health impairments and adverse health behaviors. Rather, it appears that psychiatric sequelae such as traumatic grief are of critical importance in determining which bereaved individuals will be at risk for long-term dysfunction.

A validation study of an Italian version of the brief pain inventory (Breve questionario per la valutazione del dolore)

Aim of this study was to validate the Italian version of the Brief Pain Inventory (BPI), Breve Questionario per la Valutazione del Dolore (BQVD), which is a multidimensional instrument to assess pain intensity and pain interference with daily functions. A group of 110 patients with cancer pain were enrolled in the study and were administered the BVQD and the Therapy Impact Questionnaire (TIQ) which is a valid instrument for quality of life assessment in cancer patients. Cronbach's alphas were computed for the interference and severity scales in assessing reliability. Confirmatory factor analysis was utilized to ascertain construct validity of the BQVD. Measures of interference and of intensity were calculated a priori from the TIQ results and were used in correlated correlations. Alpha coefficients for the pain severity and the pain interference scale were above 0.75. Confirmatory factor analysis showed that a 2-factor solution for the BQVD structure was interpretable and provided adequate fit for the data. The correlation with the TIQ items showed a stronger association between factor 1 (interference) and the interference with affect and activity measure from the TIQ, while factor 2 (severity) was more strongly associated with the TIQ pain severity measure. In comparison with other non-italian samples our results show a lower reliability estimate. Overall the analysis of these data shows that the BQVD is a useful and valid tool in assessing pain and its impact on patients' quality of life which could also help in developing international and cross-cultural studies in cancer pain.

SERUM PROTEINS IN RHEUMATOID DISEASE

Article1 March 1939SERUM PROTEINS IN RHEUMATOID DISEASEC. W. SCULL, Ph.D., T. F. BACH, M.D., F.A.C.P., RALPH PEMBERTON, M.D., F.A.C.P.C. W. SCULL, Ph.D.Search for more papers by this author, T. F. BACH, M.D., F.A.C.P.Search for more papers by this author, RALPH PEMBERTON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-9-1463 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONChronic arthritics present a variety of symptoms which involve deviations from normal protein metabolism.1This is graphically evident in gout, one of the smaller groups of rheumatoid disease, which is characterized by the accumulation of urates in articular and other tissues. This local feature is associated with systemic evidence of an abnormal metabolism of nucleo-protein. The absence of this conspicuous feature in the other and larger groups of rheumatoid disease has diverted attention from a consideration of such deviations in protein metabolism as are presented by them. These deviations include both local and systemic features. One large group, namely...Bibliography1. PEMBERTON R: Arthritis and rheumatoid conditions; their nature and treatment, 2nd Ed., 1935, Lea and Febiger, Philadelphia. Google Scholar2. NICHOLSRICHARDSON EHFL: Arthritis deformans, Jr. Med. Res., 1909, xxi, 149. Google Scholar3. SULLIVANHESS MXWC: The cystine content of the finger nails in arthritis, Jr. Bone and Joint Surg., 1934, xvi, 185. Google Scholar4. SCULLPEMBERTON CWR: Unpublished data. Google Scholar5. KLAUDERBROWN JVH: Sulfur content of hair and nails in abnormal states. II. Nails, Arch. Dermat. and Syph., 1935, xxxi, 26. CrossrefGoogle Scholar6. SCULLPEMBERTON CWR: The influence of dietetic and other factors on the swelling of tissues in arthritis, ANN. INT. MED., 1935, viii, 1247. LinkGoogle Scholar7. DAWSONOLMSTEADBOOTS MHMRH: Agglutination reactions in rheumatoid arthritis, Jr. Immunol., 1932, xxiii, 187. DAWSON, M. H., OLMSTEAD, M., and JOST, E. L.: Comparison of agglutinins and precipitins for Streptococcus hemolyticus in rheumatoid arthritic sera, Jr. Immunol., 1934, xxvii, 355. Google Scholar8. MARRACK JR: The chemistry of antigens and antibodies, London Med. Res. Com., Sp. Rep., 194, 1934. Google Scholar9. KAHLMETER G: Über die Bedeutung der Fahraeusschen Senkungsreaktion bei akuten und chronischen Arthritiden, Klin. Wchnschr., 1926, v, 889. CrossrefGoogle Scholar10. FAHRAEUS R: The suspension stability of blood, Physiol. Rev., 1929, ix, 241. CrossrefGoogle Scholar11. DAVIS JS: Protein studies in atrophic (rheumatoid) and hypertrophic arthritis, Jr. Lab. and Clin. Med., 1936, xxi, 478. Google Scholar12. ALRED-BROWNMUNRO GRJM: The plasma protein and non-protein nitrogen and sedimentation rate in chronic rheumatic disorders, Quart. Jr. Med., 1935, iv, 269. Google Scholar13. HAWKBERGEIM PBO: Practical physiological chemistry, 9th Ed., 1929, Blakiston, Philadelphia, p. 399. Google Scholar14. HOWE PE: The function of the plasma proteins, Physiol. Rev., 1925, v, 439. CrossrefGoogle Scholar15. BOYDBERNARD WCH: Quantitative changes in antibodies and globulin fractions in sera of rabbits injected with several antigens, Jr. Immunol., 1937, xxxiii, 111. Google Scholar16. MADDENWINSLOWHOWLANDWHIPPLE SCPMJWGH: Blood plasma protein regeneration as influenced by infection, digestive disturbance, thyroid and food proteins, Jr. Exper. Med., 1937, lxv, 431. CrossrefGoogle Scholar17. ROSE WC: The significance of the amino-acids in nutrition, Harvey Lectures, 1934-35. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication January 27, 1938.From Abington Memorial Hospital and The Graduate School of Medicine, University of Pennsylvania.The expenses of this investigation were defrayed in part by a grant in memory of Alexander B. Coxe. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLE INDAGINI SULLE CONDIZIONI EMOPROTIDO-PLASMATICHE NELLA VALUTAZIONE DEL RISCHIO CARDIOPATIE IN ASSICURAZIONE VITA, CON PARTICOLARE RIGUARDO ALLE CARDIOPATIE REUMATICHEDie pathogenetische Bedeutung der Allergie für Blut- und KnochenmarksschädenNature of collagen diseasesThe serum proteins in rheumatic diseasesTHE SERUM PROTEINS IN RHEUMATOID ARTHRITIS*ALLAN D. WALLIS, M.D.The plasma-protein fractions during the course of the disease in cases of polyarthritis rheumatica.A Study of Certain Blood Tests which reveal Colloidal Abnormalities in Rheumatic ConditionsThe Blood in Arthritis 1 March 1939Volume 12, Issue 9Page: 1463-1472KeywordsGoutGraduate medical educationHospital medicineMemoryProtein metabolismProteinsSerum proteinsUric acid ePublished: 1 December 2008 Issue Published: 1 March 1939 PDF downloadLoading ...