Abstract Usability is an important method for evaluating emerging technologies, including mobile health apps, from a user perspective. However, many apps have been made available to the public with insufficient effort devoted to their design, development and evaluation. We conducted a systematic review to assess usability evaluation and reporting for mobile health apps targeting patients with skin diseases. The primary outcome was to assess the usability of patient/public-facing skin disease-specific smartphone apps. The secondary outcome was to assess the usability testing methods employed. The protocol was registered with PROSPERO (CRD42022347184). A search strategy combined terms for usability evaluation, user experience, skin disease and mobile health apps (search date 2012–27 May 2022). Six databases (Embase, MEDLINE, CINAHL, Cochrane CENTRAL, Cochrane Database of Systematic Reviews and Scopus) were searched providing 15 234 results. Nine studies were eligible for inclusion in the final analysis. A narrative synthesis of usability evaluation methods used was reported. All studies included an equal uptake between men and women. Two studies of interest included sun protection (n = 3) and skin cancer (n = 3), and one study identified cutaneous leishmaniasis, spina bifida, chronic pruritus, acne, psoriasis, rosacea laser treatments, actinic damage, monitoring benign moles, alopecia and inflammatory rash. All studies assessed app usability and/or feasibility, with eight of nine studies concluding that their app was useful and easy to use. Most studies were qualitative, employing usability questionnaires or semi-structured interviews. Common emerging themes included easy to use/easy to navigate, easy to understand, security/privacy, method of self-monitoring, data sharing with a healthcare provider, customizability, costs and ability to track progress. The most common modules of the apps included taking/storing skin photographs, reminders to monitor skin, education modules and e-diaries/rating of symptoms. Usability encompassed various concepts, including feasibility, usefulness and satisfaction. In conclusion, smartphone apps used in the context of health-related skin disorders have a high degree of usability and are being developed across a wide variety of disease processes and indications. The paucity of reported literature compared with the current explosion of app development and deployment highlights the importance of careful user-centred design and rigorous evaluation of these tools before they are released for widespread uptake. Future studies should aim to evaluate all usability factors rather than focusing on single components of usability as this would optimize greater long-term uptake of these apps.
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